Emerging radiotherapy treatments including targeted particle therapy, hadron therapy or
radiosensitisation of cells by high-Z nanoparticles demand the theoretical determination of …

G eant 4 is a software toolkit for the simulation of the passage of particles through matter. It is
used by a large number of experiments and projects in a variety of application domains …

The Geant4-DNA project proposes to develop an open-source simulation software based
and fully included in the general-purpose Geant4 Monte-Carlo simulation toolkit. The main …

Purpose: Thegeant4 general‐purpose Monte Carlo simulation toolkit is able to simulate
physical interaction processes of electrons, hydrogen and helium atoms with charge states …

An overview of the electromagnetic (EM) physics of the Geant4 toolkit is presented. Two sets
of EM models are available: the" Standard" initially focused on high energy physics (HEP) …

Purpose: Investigation of increased radiation dose deposition due to gold nanoparticles
(GNPs) using a 3D computational cell model during x‐ray radiotherapy. Methods: Two GNP …

Simulation of biological effects of ionizing radiation at the DNA scale requires not only the
modeling of direct damages induced on DNA by the incident radiation and by secondary …

An accurate modeling of radial energy deposition around ion tracks is a key requirement of
radiation transport software used for simulations in radiobiology at the sub-cellular scale …

Purpose: This study aimed to develop a computational environment for the accurate
simulation of human cancer cell irradiation using Geant4-DNA. New cell geometrical models …

Targeted alpha therapy (TAT) has the advantage of delivering therapeutic doses to
individual cancer cells while reducing the dose to normal tissues. TAT applications relate to …