Transgenic fluorescent zebrafish lines that have revolutionized biomedical research

CP Choe, SY Choi, Y Kee, MJ Kim, SH Kim… - Laboratory Animal …, 2021 - Springer
Since its debut in the biomedical research fields in 1981, zebrafish have been used as a
vertebrate model organism in more than 40,000 biomedical research studies. Especially …

Glucose transport and transporters in the endomembranes

B Lizák, A Szarka, Y Kim, K Choi, CE Németh… - International Journal of …, 2019 - mdpi.com
Glucose is a basic nutrient in most of the creatures; its transport through biological
membranes is an absolute requirement of life. This role is fulfilled by glucose transporters …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Spns1 is a lysophospholipid transporter mediating lysosomal phospholipid salvage

M He, ACY Kuk, M Ding, CF Chin… - Proceedings of the …, 2022 - National Acad Sciences
The lysosome is central to the degradation of proteins, carbohydrates, and lipids and their
salvage back to the cytosol for reutilization. Lysosomal transporters for amino acids, sugars …

Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells

AP Ugalde, G Bretones, D Rodríguez… - The EMBO …, 2022 - embopress.org
Better understanding on interactions between SARS‐CoV‐2 and host cells should help to
identify host factors that may be targetable to combat infection and COVID‐19 pathology. To …

The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish

G Huang, F Zhang, Q Ye, H Wang - Autophagy, 2016 - Taylor & Francis
Autophagy is a highly conserved intracellular degradation system, and recently was shown
to display circadian rhythms in mice. The mechanisms underlying circadian regulation of …

1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos

XK Chen, JSK Kwan, RCC Chang, ACH Ma - Autophagy, 2021 - Taylor & Francis
phenyl 2-thiourea (PTU) is a Tyr (tyrosinase) inhibitor that is extensively used to block
pigmentation and improve optical transparency in zebrafish (Danio rerio) embryo. Here, we …

New insights on intermediary metabolism for a better understanding of nutrition in teleosts

S Panserat, L Marandel, I Seiliez… - Annual review of …, 2019 - annualreviews.org
The rapid development of aquaculture production throughout the world over the past few
decades has led to the emergence of new scientific challenges to improve fish nutrition. The …

Studying autophagy in zebrafish

BJ Mathai, AH Meijer, A Simonsen - Cells, 2017 - mdpi.com
Autophagy is an evolutionarily conserved catabolic process which allows lysosomal
degradation of complex cytoplasmic components into basic biomolecules that are recycled …

Apoptotic vesicles rejuvenate mesenchymal stem cells via Rab7-mediated autolysosome formation and alleviate bone loss in aging mice

F Lei, Z Huang, Q Ou, J Li, M Liu, L Ma, L Tan, Z Lin… - Nano Research, 2023 - Springer
Aging skeletons display decreased bone mass, increased marrow adiposity, and impaired
bone marrow mesenchymal stem cells (MSCs). Apoptosis is a programmed cell death …