Thromboembolic adverse drug reactions in Janus kinase (JAK) inhibitors: does the inhibitor specificity play a role?
PJ Kotyla, M Engelmann, J Giemza-Stokłosa… - International journal of …, 2021 - mdpi.com
Recent advances in immunology enabled the characterization of several signal transmitting
pathways responsible for proper cytokine and chemokine signaling. Among them, Janus …
pathways responsible for proper cytokine and chemokine signaling. Among them, Janus …
Acute myocardial infarction: etiologies and mimickers in young patients
C Krittanawong, M Khawaja… - Journal of the …, 2023 - Am Heart Assoc
Acute myocardial infarction is an important cause of death worldwide. While it often affects
patients of older age, acute myocardial infarction is garnering more attention as a significant …
patients of older age, acute myocardial infarction is garnering more attention as a significant …
Venous thromboembolism in total hip and total knee arthroplasty
Importance The optimal pharmacologic thromboprophylaxis agent after total hip and total
knee arthroplasty is uncertain and consensus is lacking. Quantifying the risk of postoperative …
knee arthroplasty is uncertain and consensus is lacking. Quantifying the risk of postoperative …
Etiologic subtypes of ischemic stroke in SARS-CoV-2 patients in a cohort of New York City hospitals
Objective: To describe the ischemic stroke subtypes related to coronavirus disease 2019
(COVID-19) in a cohort of New York City hospitals and explore their etiopathogenesis …
(COVID-19) in a cohort of New York City hospitals and explore their etiopathogenesis …
Using innovative machine learning methods to screen and identify predictors of congenital heart diseases
Objective: Congenital heart diseases (CHDs) are associated with an extremely heavy global
disease burden as the most common category of birth defects. Genetic and environmental …
disease burden as the most common category of birth defects. Genetic and environmental …
Comparison of hemodynamic features and thrombosis risk of membrane oxygenators with different structures: A numerical study
X Fu, Z Su, Y Wang, A Sun, L Wang, X Deng… - Computers in Biology …, 2023 - Elsevier
Purpose The geometric structure of the membrane oxygenator can exert an impact on its
hemodynamic features, which contribute to the development of thrombosis, thereby affecting …
hemodynamic features, which contribute to the development of thrombosis, thereby affecting …
Therapy development by genome editing of hematopoietic stem cells
L Koniali, CW Lederer, M Kleanthous - Cells, 2021 - mdpi.com
Accessibility of hematopoietic stem cells (HSCs) for the manipulation and repopulation of the
blood and immune systems has placed them at the forefront of cell and gene therapy …
blood and immune systems has placed them at the forefront of cell and gene therapy …
A potent anticoagulant hybrid of snake venom derived FIX-binding protein and anti-factor IX RNA aptamer: Assessed by in-silico and electrochemical analyses
H Krishnan, SCB Gopinath - International Journal of Biological …, 2023 - Elsevier
Anticoagulant therapies are crucial in the management of surgical complications as well as
the prophylaxis of thrombosis. Many studies are being conducted on the Habu snake-venom …
the prophylaxis of thrombosis. Many studies are being conducted on the Habu snake-venom …
Identification and characterization of two SERPINC1 mutations causing congenital antithrombin deficiency
H Wang, D Ruan, M Wu, Y Ji, X Hu, Q Wu, Y Zhang… - Thrombosis …, 2023 - Springer
Background Antithrombin (AT) is the main physiological anticoagulant involved in
hemostasis. Hereditary AT deficiency is a rare autosomal dominant thrombotic disease …
hemostasis. Hereditary AT deficiency is a rare autosomal dominant thrombotic disease …
Personalized modulation of coagulation factors using a thrombin dynamics model to treat trauma-induced coagulopathy
DE Ghetmiri, MJ Cohen, AA Menezes - NPJ Systems Biology and …, 2021 - nature.com
Current trauma-induced coagulopathy resuscitation protocols use slow laboratory
measurements, rules-of-thumb, and clinician gestalt to administer large volumes of …
measurements, rules-of-thumb, and clinician gestalt to administer large volumes of …