Resolution pharmacology: focus on pro-resolving annexin A1 and lipid mediators for therapeutic innovation in inflammation

M Perretti, J Dalli - Annual Review of Pharmacology and …, 2023 - annualreviews.org
Chronic diseases that affect our society are made more complex by comorbidities and are
poorly managed by the current pharmacology. While all present inflammatory …

Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease

G Fredman, CN Serhan - Nature Reviews Cardiology, 2024 - nature.com
Timely resolution of the acute inflammatory response (or inflammation resolution) is an
active, highly coordinated process that is essential to optimal health. Inflammation resolution …

Resolvins and cysteinyl-containing pro-resolving mediators activate resolution of infectious inflammation and tissue regeneration

CN Serhan, N Chiang - Prostaglandins & other lipid mediators, 2023 - Elsevier
This review is a synopsis of the main points from the opening presentation by the authors in
the Resolution of Inflammation session at the 8th European Workshop on Lipid Mediators …

Illuminating the oral microbiome and its host interactions: animal models of disease

G Hajishengallis - FEMS Microbiology Reviews, 2023 - academic.oup.com
Periodontitis and caries are driven by complex interactions between the oral microbiome
and host factors, ie inflammation and dietary sugars, respectively. Animal models have been …

Pneumonia-induced inflammation, resolution and cardiovascular disease: causes, consequences and clinical opportunities

C Stotts, VF Corrales-Medina, KJ Rayner - Circulation research, 2023 - Am Heart Assoc
Pneumonia is inflammation in the lungs, which is usually caused by an infection. The
symptoms of pneumonia can vary from mild to life-threatening, where severe illness is often …

Roles of resolvins in chronic inflammatory response

C Liu, D Fan, Q Lei, A Lu, X He - International journal of molecular …, 2022 - mdpi.com
An inflammatory response is beneficial to the organism, while an excessive uncontrolled
inflammatory response can lead to the nonspecific killing of tissue cells. Therefore …

Resolvin D2 attenuates cardiovascular damage in angiotensin II-induced hypertension

LS Díaz del Campo, AB García-Redondo… - …, 2023 - Am Heart Assoc
Background: Resolution of inflammation is orchestrated by specialized proresolving lipid
mediators (SPMs), and this would be impaired in some cardiovascular diseases. Among …

Polyunsaturated fatty acids and metabolic health: novel insights

I Djuricic, PC Calder - Current Opinion in Clinical Nutrition & …, 2022 - journals.lww.com
Polyunsaturated fatty acids and metabolic health: novel insi... : Current Opinion in Clinical
Nutrition & Metabolic Care Polyunsaturated fatty acids and metabolic health: novel insights …

Role of resolvins in inflammatory and neuropathic pain

J Park, J Roh, J Pan, YH Kim, CK Park, YY Jo - Pharmaceuticals, 2023 - mdpi.com
Chronic pain is an unpleasant experience associated with actual or potential tissue damage.
Inflammatory pain alerts the body to inflammation and promotes healing; however …

Prolonged experimental sleep disturbance affects the inflammatory resolution pathways in healthy humans

LC Engert, JM Mullington, M Haack - Brain, Behavior, and Immunity, 2023 - Elsevier
Background Sleep disturbances, as manifested in insomnia symptoms of difficulties falling
asleep or frequent nighttime awakenings, are a strong risk factor for a diverse range of …