[HTML][HTML] MicroRNAs as modulators and biomarkers of inflammatory and neuropathic pain conditions
HH Andersen, M Duroux, P Gazerani - Neurobiology of Disease, 2014 - Elsevier
The post-transcriptional regulator molecules, microRNAs, have emerged as important
biomarkers and modulators of numerous pathophysiological processes including …
biomarkers and modulators of numerous pathophysiological processes including …
Epigenetic regulation of chronic pain
Chronic pain arising from peripheral inflammation and tissue or nerve injury is a common
clinical symptom. Although intensive research on the neurobiological mechanisms of …
clinical symptom. Although intensive research on the neurobiological mechanisms of …
[HTML][HTML] A nerve injury–specific long noncoding RNA promotes neuropathic pain by increasing Ccl2 expression
Maladaptive changes of nerve injury–associated genes in dorsal root ganglia (DRGs) are
critical for neuropathic pain genesis. Emerging evidence supports the role of long noncoding …
critical for neuropathic pain genesis. Emerging evidence supports the role of long noncoding …
[HTML][HTML] DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons
Nerve injury induces changes in gene transcription in dorsal root ganglion (DRG) neurons,
which may contribute to nerve injury-induced neuropathic pain. DNA methylation represses …
which may contribute to nerve injury-induced neuropathic pain. DNA methylation represses …
N6‐Methyladenosine Demethylase FTO Contributes to Neuropathic Pain by Stabilizing G9a Expression in Primary Sensory Neurons
Nerve injury‐induced change in gene expression in primary sensory neurons of dorsal root
ganglion (DRG) is critical for neuropathic pain genesis. N6‐methyladenosine (m6A) …
ganglion (DRG) is critical for neuropathic pain genesis. N6‐methyladenosine (m6A) …
Downregulation of a dorsal root ganglion‐specifically enriched long noncoding RNA is required for neuropathic pain by negatively regulating RALY‐triggered Ehmt2 …
Nerve injury‐induced maladaptive changes of gene expression in dorsal root ganglion
(DRG) neurons contribute to neuropathic pain. Long non‐coding RNAs (lncRNAs) are …
(DRG) neurons contribute to neuropathic pain. Long non‐coding RNAs (lncRNAs) are …
Long noncoding RNA (lncRNA): a target in neuropathic pain
Introduction: Current treatments for neuropathic pain are limited in part due to the incomplete
understanding of its underlying mechanisms. Recent evidence reveals the dysregulated …
understanding of its underlying mechanisms. Recent evidence reveals the dysregulated …
Histone methylation-mediated microRNA-32-5p down-regulation in sensory neurons regulates pain behaviors via targeting Cav3. 2 channels
R Qi, J Cao, Y Sun, Y Li, Z Huang… - Proceedings of the …, 2022 - National Acad Sciences
microRNA (miRNA)–mediated gene regulation has been studied as a therapeutic approach,
but its functional regulatory mechanism in neuropathic pain is not well understood. Here, we …
but its functional regulatory mechanism in neuropathic pain is not well understood. Here, we …
Transcription factor EBF1 mitigates neuropathic pain by rescuing Kv1. 2 expression in primary sensory neurons
Y Liang, D Sharma, B Wang, H Wang, X Feng… - Translational …, 2024 - Elsevier
Nerve injury-induced alternations of gene expression in primary sensory neurons of the
dorsal root ganglion (DRG) are molecular basis of neuropathic pain genesis. Transcription …
dorsal root ganglion (DRG) are molecular basis of neuropathic pain genesis. Transcription …
[HTML][HTML] The importance of the gut microbiome and its signals for a healthy nervous system and the multifaceted mechanisms of neuropsychiatric disorders
L Riehl, J Fürst, M Kress, N Rykalo - Frontiers in Neuroscience, 2024 - frontiersin.org
Increasing evidence links the gut microbiome and the nervous system in health and disease.
This narrative review discusses current views on the interaction between the gut microbiota …
This narrative review discusses current views on the interaction between the gut microbiota …