The effects of trauma on brain and body: A unifying role for the midbrain periaqueductal gray

BA Terpou, S Harricharan… - Journal of …, 2019 - Wiley Online Library
Post‐traumatic stress disorder (PTSD), a diagnosis that may follow the experience of trauma,
has multiple symptomatic phenotypes. Generally, individuals with PTSD display symptoms …

Borderline personality disorder: a dysregulation of the endogenous opioid system?

B Bandelow, C Schmahl, P Falkai… - Psychological …, 2010 - psycnet.apa.org
The neurobiology of borderline personality disorder (BPD) remains unclear. Dysfunctions of
several neurobiological systems, including serotoninergic, dopaminergic, and other …

GABA receptors, progesterone and premenstrual dysphoric disorder

I Sundström Poromaa, S Smith, M Gulinello - Archives of women's mental …, 2003 - Springer
Premenstrual dysphoric disorder (PMDD) is characterized by depression, anxiety and other
affective symptoms which recur in the luteal phase of the menstrual cycle. Evidence from …

Opioids and anxiety

A Colasanti, EA Rabiner… - Journal of …, 2011 - journals.sagepub.com
The opioid system plays a crucial role in the neural modulation of anxiety. The involvement
of opioid ligands and receptors in physiological and dysfunctional forms of anxiety is …

A critical review on the participation of inferior colliculus in acoustic-motor and acoustic-limbic networks involved in the expression of acute and kindled audiogenic …

N Garcia-Cairasco - Hearing research, 2002 - Elsevier
The main goal of this article is to review the key role that the inferior colliculus plays in the
expression of acoustic-motor and acoustic-limbic integration involved, respectively, in acute …

The relevance of neuronal substrates of defense in the midbrain tectum to anxiety and stress: empirical and conceptual considerations

ML Brandão, AC Troncoso, MA de Souza Silva… - European journal of …, 2003 - Elsevier
The medial hypothalamus, amygdala, and dorsal periaqueductal gray constitute the main
neural substrates for the integration of aversive states in the brain. More recently, some …

Anti-aversive effects of cannabidiol on innate fear-induced behaviors evoked by an ethological model of panic attacks based on a prey vs the wild snake Epicrates …

A Uribe-Marino, A Francisco… - …, 2012 - nature.com
Several pharmacological targets have been proposed as modulators of panic-like reactions.
However, interest should be given to other potential therapeutic neurochemical agents …

Neuroanatomical approaches of the tectum-reticular pathways and immunohistochemical evidence for serotonin-positive perikarya on neuronal substrates of the …

NC Coimbra, R De Oliveira, RL Freitas, SJ Ribeiro… - Experimental …, 2006 - Elsevier
Deep layers of the superior colliculus, the dorsal periaqueductal gray matter and the inferior
colliculus are midbrain structures involved in the generation of defensive behavior and fear …

fMRI measurement of CNS responses to naloxone infusion and subsequent mild noxious thermal stimuli in healthy volunteers

MC Borras, L Becerra, A Ploghaus… - Journal of …, 2004 - journals.physiology.org
The aims of this study were to assess the effects of a μ-opioid antagonist, naloxone, on
endogenous opioid systems and to evaluate the effect of naloxone on the CNS response to …

The periaqueductal gray and its extended participation in drug addiction phenomena

P Vázquez-León, A Miranda-Páez… - Neuroscience …, 2021 - Springer
The periaqueductal gray (PAG) is a complex mesencephalic structure involved in the
integration and execution of active and passive self-protective behaviors against imminent …