Myocardial infarction (MI) is the irreversible death of cardiomyocyte secondary to prolonged
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …

Acute myocardial infarction (AMI) and the heart failure (HF) that often follows are among the
leading causes of death and disability worldwide. As such, new treatments are needed to …

Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes,
and can accelerate diabetes-related microvascular and macrovascular complications by …

Cardiovascular disease is a major leading cause of morbidity and mortality in the United
States and elsewhere. Alterations in mitochondrial function are increasingly being …

Acute myocardial infarction is the leading cause of cardiovascular‑related mortality and
chronic heart failure worldwide. As regards treatment, the reperfusion of ischemic tissue …

The central functions fulfilled by mitochondria as both energy generators essential for tissue
homeostasis and gateways to programmed apoptotic and necrotic cell death mandate tight …

Mitochondria are highly dynamic, except in adult cardiomyocytes. Yet, the fission and fusion-
promoting proteins that mediate mitochondrial dynamism are highly expressed in, and …

Mitochondria play an important role in maintaining cardiac homeostasis by supplying the
major energy required for cardiac excitation–contraction coupling as well as controlling the …

Healthy mitochondrial function is imperative for most tissues, but especially those with a high
energy demand. Robust evidence linking mitochondrial dysfunction with cardiovascular …

Mitochondrial quality is a crucial determinant of cell viability, and mitochondrial autophagy
plays a central role in this control mechanism. Based on studies in yeast, numerous …