Innate-immunity genes in obesity
SV Mikhailova, DE Ivanoshchuk - Journal of personalized medicine, 2021 - mdpi.com
The main functions of adipose tissue are thought to be storage and mobilization of the
body's energy reserves, active and passive thermoregulation, participation in the spatial …
body's energy reserves, active and passive thermoregulation, participation in the spatial …
Ameliorating Effect of the Total Flavonoids of Morus nigra L. on Prediabetic Mice Based on Regulation of Inflammation and Insulin Sensitization
X Ren, Y Sun, Q Guo, H Liu, H Jiang, X He… - Journal of Agricultural …, 2022 - ACS Publications
Prediabetes is a critical stage characterized by insulin resistance. Morus nigra L., an edible
plant, is widely used in food and nutritive supplements and exhibits various pharmacological …
plant, is widely used in food and nutritive supplements and exhibits various pharmacological …
Combinational application of the natural products 1-deoxynojirimycin and morin ameliorates insulin resistance and lipid accumulation in prediabetic mice
X Ren, Q Guo, H Jiang, X Han, X He, H Liu, Z Xiu… - Phytomedicine, 2023 - Elsevier
Background Prediabetes, a stage characterized by chronic inflammation, obesity and insulin
resistance. Morin and 1-deoxynojirimycin (DNJ) are natural flavonoids and alkaloids …
resistance. Morin and 1-deoxynojirimycin (DNJ) are natural flavonoids and alkaloids …
Identification and immunological characterization of lipid metabolism-related molecular clusters in nonalcoholic fatty liver disease
J Liu, Y Li, J Ma, X Wan, M Zhao, Y Zhang… - Lipids in Health and …, 2023 - Springer
Background Nonalcoholic fatty liver disease (NAFLD) is now the major contributor to chronic
liver disease. Disorders of lipid metabolism are a major element in the emergence of …
liver disease. Disorders of lipid metabolism are a major element in the emergence of …
RPL38 knockdown inhibits the inflammation and apoptosis in chondrocytes through regulating METTL3-mediated SOCS2 m6A modification in osteoarthritis
L Shi, H Hu, P Sun, Z Li, L Ji, S Liu, J Zhang - Inflammation Research, 2022 - Springer
Abstract Background Ribosomal protein L38 (RPL38) was found upregulated in
osteoarthritic peripheral blood mononuclear cells, however, its role in progression of …
osteoarthritic peripheral blood mononuclear cells, however, its role in progression of …
[HTML][HTML] The immunoregulatory role of fish specific type II SOCS via inhibiting metaflammation in the gut-liver axis
J Shan, G Wang, H Li, X Zhao, W Ye, L Su, Q Zhu… - Water Biology and …, 2023 - Elsevier
SOCS8, also known as CISHb, is a fish-specific type II SOCS. Because CISH binds to
cytokine receptors and may inhibit STAT5 activation (a substrate of the insulin receptor) …
cytokine receptors and may inhibit STAT5 activation (a substrate of the insulin receptor) …
Molecular and metabolic analysis of arsenic-exposed humanized AS3MT mice
J Todero, C Douillet, AJ Shumway… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Chronic exposure to inorganic arsenic (iAs) has been associated with type 2
diabetes (T2D). However, potential sex divergence and the underlying mechanisms remain …
diabetes (T2D). However, potential sex divergence and the underlying mechanisms remain …
[HTML][HTML] Identification of potential feature genes in non-alcoholic fatty liver disease using bioinformatics analysis and machine learning strategies
Z Zhang, S Wang, Z Zhu, B Nie - Computers in Biology and Medicine, 2023 - Elsevier
The prevalence of non-alcoholic fatty liver disease (NAFLD) and NAFLD-associated
hepatocellular carcinoma (HCC) has continuously increased in recent years. Machine …
hepatocellular carcinoma (HCC) has continuously increased in recent years. Machine …
Gene expression associations with body mass index in the Multi-Ethnic Study of Atherosclerosis
Background/objectives Obesity, defined as excessive fat accumulation that represents a
health risk, is increasing in adults and children, reaching global epidemic proportions. Body …
health risk, is increasing in adults and children, reaching global epidemic proportions. Body …
Cytokine‐inducible SH2 domain containing protein contributes to regulation of adiposity, food intake, and glucose metabolism
The cytokine‐inducible SH2 domain containing protein (CISH) is the founding member of
the suppressor of cytokine signaling (SOCS) family of negative feedback regulators and has …
the suppressor of cytokine signaling (SOCS) family of negative feedback regulators and has …