Inflammatory bowel disease in pregnancy and breastfeeding
MN Brondfield, U Mahadevan - Nature Reviews Gastroenterology & …, 2023 - nature.com
Inflammatory bowel disease (IBD) has a peak age of diagnosis before the age of 35 years.
Concerns about infertility, adverse pregnancy outcomes, and heritability of IBD have …
Concerns about infertility, adverse pregnancy outcomes, and heritability of IBD have …
European Crohn's and colitis guidelines on sexuality, fertility, pregnancy, and lactation
J Torres, M Chaparro, M Julsgaard… - Journal of Crohn's …, 2023 - academic.oup.com
2. Methods This document represents the third version of the European Consensus on
reproduction in IBD. The development of this Consensus included the formulation of …
reproduction in IBD. The development of this Consensus included the formulation of …
New drugs for the treatment of IBD during conception, pregnancy, and lactation
The management of inflammatory bowel disease requires continuous medical therapy to
achieve and maintain disease control. Thus, women can be exposed to different drugs …
achieve and maintain disease control. Thus, women can be exposed to different drugs …
Safety of ustekinumab and vedolizumab during pregnancy—pregnancy, neonatal, and infant outcome: A prospective multicentre study
K Mitrova, B Pipek, M Bortlik, L Bouchner… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Evidence on the safety of newer biologics during pregnancy
is limited. We aimed to assess the safety of ustekinumab and vedolizumab treatment during …
is limited. We aimed to assess the safety of ustekinumab and vedolizumab treatment during …
[HTML][HTML] Infant ustekinumab clearance, risk of infection, and development after exposure during pregnancy
M Julsgaard, JW Wieringa, SMD Baunwall… - Clinical …, 2025 - Elsevier
Background Evidence on ustekinumab safety in pregnancy is gradually expanding, but its
clearance in the postnatal period is unknown. The aim of this study was to investigate …
clearance in the postnatal period is unknown. The aim of this study was to investigate …
Pregnancy outcomes following periconceptional or gestational exposure to ustekinumab: Review of cases reported to the manufacturer's global safety database
U Mahadevan, S Naureckas, I Tikhonov… - Alimentary …, 2022 - Wiley Online Library
Background Ustekinumab, a human immunoglobulin G1 monoclonal antibody that binds to
and inhibits interleukin (IL)‐12/IL‐23, is indicated for multiple immune‐mediated diseases …
and inhibits interleukin (IL)‐12/IL‐23, is indicated for multiple immune‐mediated diseases …
Vedolizumab and ustekinumab levels in pregnant women with inflammatory bowel disease and infants exposed in utero
Background & Aims Vedolizumab and ustekinumab pharmacokinetics in pregnancy and the
infant after in utero exposure remain incompletely defined. We aim to define the antenatal …
infant after in utero exposure remain incompletely defined. We aim to define the antenatal …
Australian inflammatory bowel disease consensus statements for preconception, pregnancy and breast feeding
Objective Because pregnancy outcomes tend to be worse in women with inflammatory
bowel disease (IBD) than in those without, we aimed to update consensus statements that …
bowel disease (IBD) than in those without, we aimed to update consensus statements that …
Vaccines in Children Exposed to Biological Agents In Utero and/or During Breastfeeding: Are They Effective and Safe?
JP Gisbert, M Chaparro - Journal of Crohn's and Colitis, 2023 - academic.oup.com
Background Biological agents cross the placenta, resulting in detectable blood levels in the
neonate. Neonatal vaccinations are essential to prevent serious infections. Aim To review …
neonate. Neonatal vaccinations are essential to prevent serious infections. Aim To review …
Maternal and Neonatal Outcomes in Vedolizumab-and Ustekinumab-Exposed Pregnancies: Results From the PIANO Registry
R Chugh, MD Long, Y Jiang, KN Weaver… - Official journal of the …, 2022 - journals.lww.com
Background: Pregnancy outcomes in patients with inflammatory bowel disease with
quiescent disease are similar to those in the general population. Data from the Pregnancy …
quiescent disease are similar to those in the general population. Data from the Pregnancy …