Dementia prevention, intervention, and care

G Livingston, A Sommerlad, V Orgeta, SG Costafreda… - The lancet, 2017 - thelancet.com
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

Education and dementia in the context of the cognitive reserve hypothesis: a systematic review with meta-analyses and qualitative analyses

X Meng, C D'arcy - PloS one, 2012 - journals.plos.org
Background Cognitive reserve (CR) or brain reserve capacity explains why individuals with
higher IQ, education, or occupational attainment have lower risks of developing dementia …

Population attributable fractions for risk factors for dementia in low-income and middle-income countries: an analysis using cross-sectional survey data

N Mukadam, A Sommerlad, J Huntley… - The Lancet Global …, 2019 - thelancet.com
Background Nine potentially modifiable risk factors (less childhood education, midlife
hearing loss, hypertension, and obesity, and later-life smoking, depression, physical …

Sex differences in cognitive impairment and Alzheimer's disease

R Li, M Singh - Frontiers in neuroendocrinology, 2014 - Elsevier
Studies have shown differences in specific cognitive ability domains and risk of Alzheimer's
disease between the men and women at later age. However it is important to know that sex …

The prevalence and incidence of dementia due to Alzheimer's disease: a systematic review and meta-analysis

KM Fiest, JI Roberts, CJ Maxwell, DB Hogan… - Canadian Journal of …, 2016 - cambridge.org
BackgroundUpdated information on the epidemiology of dementia due to Alzheimer's
disease (AD) is needed to ensure that adequate resources are available to meet current and …

The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy

PL McGeer, EG McGeer - Acta neuropathologica, 2013 - Springer
The amyloid cascade hypothesis is widely accepted as the centerpiece of Alzheimer
disease (AD) pathogenesis. It proposes that abnormal production of beta amyloid protein …

Impact of physical activity on cognitive decline, dementia, and its subtypes: meta‐analysis of prospective studies

CB Guure, NA Ibrahim, MB Adam… - BioMed research …, 2017 - Wiley Online Library
The association of physical activity with dementia and its subtypes has remained
controversial in the literature and has continued to be a subject of debate among …

Diabetes mellitus and the risk of dementia: The Rotterdam Study

A Ott, RP Stolk, F Van Harskamp, HAP Pols, A Hofman… - Neurology, 1999 - AAN Enterprises
Objective: To determine the influence of type 2 diabetes mellitus on the risk of dementia and
AD. Background: Both dementia and diabetes are frequent disorders in elderly people …

Prevalence of dementia in the United States: the aging, demographics, and memory study

BL Plassman, KM Langa, GG Fisher, SG Heeringa… - …, 2007 - karger.com
Aim: To estimate the prevalence of Alzheimer's disease (AD) and other dementias in the
USA using a nationally representative sample. Methods: The Aging, Demographics, and …

Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset.

R Brookmeyer, S Gray… - American journal of …, 1998 - ajph.aphapublications.org
OBJECTIVES: The goal of this study was to project the future prevalence and incidence of
Alzheimer's disease in the United States and the potential impact of interventions to delay …