Abstract SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), is
responsible for the largest pandemic facing humanity since the Spanish flu pandemic in the …

Rationale Acute respiratory distress syndrome (ARDS) is frequently associated with
hemodynamic instability which appears as the main factor associated with mortality. Shock …

Primary graft dysfunction (PGD) refers to the syndrome of acute lung injury early after lung
transplantation (LTx). 1 In 2005, based on the need for a reliable and valid definition with …

Over the past decade, science has greatly advanced our understanding of interdependent
feedback mechanisms involving the heart, lung, and kidney. Organ injury is the …

Objectives: The objectives of this study were to evaluate the efficacy and safety of inhaled
epoprostenol and inhaled nitric oxide in patients with refractory hypoxemia secondary to …

Pulmonary hypertension (PH) is a severe disease that affects people of all ages. It can occur
as an idiopathic disorder at birth or as part of a variety of cardiovascular and pulmonary …

Objectives: To describe the current state of the art regarding management of the critically ill
trauma patient with an emphasis on initial management in the ICU. Data Sources and Study …

In this Series paper, we review the current evidence for the use of high-flow oxygen therapy,
inhaled gases, and aerosols in the care of critically ill patients. The available evidence …

Acute respiratory failure is commonly encountered in the emergency department (ED), and
early treatment can have effects on long-term outcome. Noninvasive ventilation is commonly …

Asthma, acute lung injury (ALI), and chronic obstructive pulmonary disease (COPD) are lung
inflammatory disorders with a common outcome, that is, difficulty in breathing …