Potential SARS-CoV-2 main protease inhibitors
R Banerjee, L Perera, LMV Tillekeratne - Drug Discovery Today, 2021 - Elsevier
Highlights•The SARS-CoV-2 main protease is a prime drug target.•Coronavirus main
proteases share a structurally conserved substrate-binding region.•The structure and …
proteases share a structurally conserved substrate-binding region.•The structure and …
Revealing the potency of citrus and galangal constituents to halt SARS-CoV-2 infection
COVID-19 pandemic is a serious problem in the world today. The SARS-CoV-2 virus that
causes COVID-19 has important proteins used for its infection and development, namely the …
causes COVID-19 has important proteins used for its infection and development, namely the …
Soft computing techniques for biomedical data analysis: open issues and challenges
EH Houssein, ME Hosney, MM Emam… - Artificial Intelligence …, 2023 - Springer
In recent years, medical data analysis has become paramount in delivering accurate
diagnoses for various diseases. The plethora of medical data sources, encompassing …
diagnoses for various diseases. The plethora of medical data sources, encompassing …
Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CLpro
The SARS-CoV-2 was confirmed to cause the global pandemic of coronavirus disease 2019
(COVID-19). The 3-chymotrypsin-like protease (3CLpro), an essential enzyme for viral …
(COVID-19). The 3-chymotrypsin-like protease (3CLpro), an essential enzyme for viral …
Investigating Potential Inhibitory Effect of Uncaria tomentosa (Cat's Claw) against the Main Protease 3CLpro of SARS‐CoV‐2 by Molecular Modeling
AF Yepes-Pérez, O Herrera-Calderon… - Evidence‐Based …, 2020 - Wiley Online Library
COVID‐19 is a disease caused by severe acute respiratory syndrome coronavirus 2.
Presently, there is no effective treatment for COVID‐19. As part of the worldwide efforts to …
Presently, there is no effective treatment for COVID‐19. As part of the worldwide efforts to …
[HTML][HTML] Natural compounds as inhibitors of SARS-CoV-2 endocytosis: A promising approach against COVID-19
AK Kiani, K Dhuli, K Anpilogov, S Bressan… - Acta Bio Medica …, 2020 - ncbi.nlm.nih.gov
Methods: We performed the literature search for these natural compounds in the articles
indexed in PubMed. Results: Natural products against viral infections have been gaining …
indexed in PubMed. Results: Natural products against viral infections have been gaining …
Protein reliability analysis and virtual screening of natural inhibitors for SARS-CoV-2 main protease (Mpro) through docking, molecular mechanic & dynamic, and …
K Kapusta, S Kar, JT Collins, LM Franklin… - Journal of …, 2021 - Taylor & Francis
Due to an outbreak of COVID-19, the number of research papers devoted to in-silico drug
discovery of potential antiviral drugs is increasing every day exponentially. Still, there is no …
discovery of potential antiviral drugs is increasing every day exponentially. Still, there is no …
Exploring the anti-SARS-CoV-2 main protease potential of FDA approved marine drugs using integrated machine learning templates as predictive tools
Since the inception of COVID-19 pandemic in December 2019, socio-economic crisis begins
to rise globally and SARS-CoV-2 was responsible for this outbreak. With this outbreak …
to rise globally and SARS-CoV-2 was responsible for this outbreak. With this outbreak …
Demystifying excess immune response in COVID-19 to reposition an orphan drug for down-regulation of NF-κB: a systematic review
A Peddapalli, M Gehani, AM Kalle, SR Peddapalli… - Viruses, 2021 - mdpi.com
The immunological findings from autopsies, biopsies, and various studies in COVID-19
patients show that the major cause of morbidity and mortality in COVID-19 is excess immune …
patients show that the major cause of morbidity and mortality in COVID-19 is excess immune …
KORONAVİRÜSLE (COVİD-19) MÜCADELEDE BESLENMENİN BAĞIŞIKLIK SİSTEMİNİN DESTEKLENMESİNDE ROLÜ
Yeni koronavius hastalığı “COVID-19” dünyada birçok insanın hayatını tehdit eden ciddi bir
halk sağlığı sorunu olmuştur. Bu yeni virüsten korunmada veya hastalık şiddetini …
halk sağlığı sorunu olmuştur. Bu yeni virüsten korunmada veya hastalık şiddetini …