Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Targeted anticancer drugs block cancer cell growth by interfering with specific signaling
pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing …

There is a need for in vivo diagnostic imaging probes that can noninvasively measure tumor-
infiltrating CD8+ leukocytes. Such imaging probes could be used to predict early response …

Simple Summary Monoclonal antibodies (mAbs) have the ability to specifically target tumor-
cell antigens. This unique property has led to their use in the delivery of radioisotopes to …

Breast cancer is a major disease with high morbidity and mortality in women worldwide.
Increased use of imaging biomarkers has been shown to add more information with clinical …

89Zr is an emerging radionuclide that plays an essential role in immuno-positron emission
tomography (PET) imaging. The long half-life of 89Zr (t1/2= 3.3 days) is favorable for …

The determination of tumor human epidermal growth factor receptor type 2 (HER2) status is
of increasing importance with the recent approval of more efficacious HER2-targeted …

OBJECTIVE. FDG PET/CT affects the management of patients with breast cancer in multiple
settings, including initial staging, treatment response assessment, and evaluation of …

Background Current measurements of multiple myeloma disease burden are suboptimal.
Daratumumab is a monoclonal antibody that targets CD38, an antigen expressed on nearly …