Prospective of nanoscale metal organic frameworks [NMOFs] for cancer therapy
Nano metal organic frameworks (NMOFs) belong to the group of nanoporous materials.
Over the decades, the conducted researches explored the area for the potential applications …
Over the decades, the conducted researches explored the area for the potential applications …
Influence and effect of osmolytes in biopharmaceutical formulations
SR Wlodarczyk, D Custódio, A Pessoa Jr… - European Journal of …, 2018 - Elsevier
Osmolytes are small organic molecules accumulated by cells in response to environmental
stresses. They are represented by amino acids, sugars, polyols, tertiary sulphonium and …
stresses. They are represented by amino acids, sugars, polyols, tertiary sulphonium and …
Evaluation of interactions between food colorant, tartrazine, and Apo-transferrin using spectroscopic analysis and docking simulation
H Jafari-Arvari, SS Saei-Dehkordi… - Journal of Molecular …, 2021 - Elsevier
Colors are one of the most widely used additives in the food industry. Despite the fact that
tartrazine, which is an artificial synthetic acid azo dye, has frequently been used worldwide …
tartrazine, which is an artificial synthetic acid azo dye, has frequently been used worldwide …
Protective actions of bioactive flavonoids chrysin and luteolin on the glyoxal induced formation of advanced glycation end products and aggregation of human serum …
The post-translational modification of proteins by nonenzymatic glycation (NEG) and the
accumulation of AGEs are the two underlying factors associated with the long-term …
accumulation of AGEs are the two underlying factors associated with the long-term …
Interaction of new kinase inhibitors cabozantinib and tofacitinib with human serum alpha-1 acid glycoprotein. A comprehensive spectroscopic and molecular Docking …
MR Ajmal, AS Abdelhameed, P Alam… - Spectrochimica Acta Part A …, 2016 - Elsevier
In the current study we have investigated the interaction of newly approved kinase inhibitors
namely Cabozantinib (CBZ) and Tofacitinib (TFB) with human Alpha-1 acid glycoprotein …
namely Cabozantinib (CBZ) and Tofacitinib (TFB) with human Alpha-1 acid glycoprotein …
Development of a reliable microRNA based electrochemical genosensor for monitoring of miR-146a, as key regulatory agent of neurodegenerative disease
A MicroRNA (miR) based electrochemical method for quantification of miR-146a, a known
biomarker for neurodegenerative disease, was developed. In this bioassay, the capture …
biomarker for neurodegenerative disease, was developed. In this bioassay, the capture …
Mitigation of ribose and glyoxal induced glycation, AGEs formation and aggregation of human serum albumin by citrus fruit phytochemicals naringin and naringenin …
Human serum albumin (HSA) being the most prevalent protein in the plasma is extremely
vulnerable to glycation. Two flavonoids naringin and naringenin were tested for their effects …
vulnerable to glycation. Two flavonoids naringin and naringenin were tested for their effects …
Diverse effects of aqueous polar co-solvents on Candida antarctica lipase B
Biocatalysis in mixtures of water and co-solvents represents an opportunity to expand the
application of enzymes. However, in the presence of organic solvents, enzymes can …
application of enzymes. However, in the presence of organic solvents, enzymes can …
Comparative study of the protein denaturing ability of different organic cosolvents
T Magsumov, L Ziying, I Sedov - International Journal of Biological …, 2020 - Elsevier
The influence of a wide spectrum of water-miscible organic cosolvents at different
concentrations on the denaturation of hen egg-white lysozyme is studied using differential …
concentrations on the denaturation of hen egg-white lysozyme is studied using differential …
Carvacrol protects against carbonyl osmolyte-induced structural modifications and aggregation to serum albumin: Insights from physicochemical and molecular …
The robust use of osmolytes (ie, polyols and sugars) in the key therapeutic
regimens/formulations has questioned their impact beyond the stability of therapeutic …
regimens/formulations has questioned their impact beyond the stability of therapeutic …