Tularemia: history, epidemiology, pathogen physiology, and clinical manifestations
A Sjöstedt - Annals of the New York Academy of Sciences, 2007 - Wiley Online Library
Francisella tularensis has been recognized as a human pathogen for almost 100 years and
is the etiological agent of the zoonotic disease tularemia. Soon after its discovery, it became …
is the etiological agent of the zoonotic disease tularemia. Soon after its discovery, it became …
Tularaemia: bioterrorism defence renews interest in Francisella tularensis
PCF Oyston, A Sjöstedt, RW Titball - Nature Reviews Microbiology, 2004 - nature.com
Francisella tularensis is a highly infectious aerosolizable intracellular pathogen that is
capable of causing a debilitating or fatal disease with doses as low as 25 colony-forming …
capable of causing a debilitating or fatal disease with doses as low as 25 colony-forming …
Survival and Growth of Francisella tularensis in Acanthamoeba castellanii
H Abd, T Johansson, I Golovliov… - Applied and …, 2003 - Am Soc Microbiol
Francisella tularensis is a highly infectious, facultative intracellular bacterium which causes
epidemics of tularemia in both humans and mammals at regular intervals. The natural …
epidemics of tularemia in both humans and mammals at regular intervals. The natural …
Virulent and Avirulent Strains of Francisella tularensis Prevent Acidification and Maturation of Their Phagosomes and Escape into the Cytoplasm in Human …
DL Clemens, BY Lee, MA Horwitz - Infection and immunity, 2004 - Am Soc Microbiol
Francisella tularensis, the agent of tularemia, is an intracellular pathogen, but little is known
about the compartment in which it resides in human macrophages. We have examined the …
about the compartment in which it resides in human macrophages. We have examined the …
Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication
C Checroun, TD Wehrly, ER Fischer… - Proceedings of the …, 2006 - National Acad Sciences
Intracellular bacterial pathogens evade the bactericidal functions of mammalian cells by
physical escape from their phagosome and replication into the cytoplasm or through the …
physical escape from their phagosome and replication into the cytoplasm or through the …
Differential roles of caspase-1 and caspase-11 in infection and inflammation
Caspase-1, also known as interleukin-1β (IL-1β)-converting enzyme (ICE), regulates
antimicrobial host defense, tissue repair, tumorigenesis, metabolism and membrane …
antimicrobial host defense, tissue repair, tumorigenesis, metabolism and membrane …
Strategies used by bacteria to grow in macrophages
G Mitchell, C Chen, DA Portnoy - Myeloid Cells in Health and …, 2017 - Wiley Online Library
Intracellular bacterial pathogens cause a wide range of diseases and significantly contribute
to the morbidity and mortality associated with infectious diseases worldwide (1‐16)(Table 1) …
to the morbidity and mortality associated with infectious diseases worldwide (1‐16)(Table 1) …
An Attenuated Strain of the Facultative Intracellular Bacterium Francisella tularensis Can Escape the Phagosome of Monocytic Cells
I Golovliov, V Baranov, Z Krocova… - Infection and …, 2003 - Am Soc Microbiol
The facultative intracellular bacterium Francisella tularensis is a highly virulent and
contagious organism, and little is known about its intracellular survival mechanisms. We …
contagious organism, and little is known about its intracellular survival mechanisms. We …
Modulation of phagocyte apoptosis by bacterial pathogens
FR DeLeo - Apoptosis, 2004 - Springer
Phagocytic leukocytes such as neutrophils and macrophages are essential for the innate
immune response against invading bacteria. Binding and ingestion of bacteria by these host …
immune response against invading bacteria. Binding and ingestion of bacteria by these host …
MglA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival
Francisella tularensis is able to survive and grow within macrophages, a trait that contributes
to pathogenesis. Several genes have been identified that are important for intramacrophage …
to pathogenesis. Several genes have been identified that are important for intramacrophage …