Yeast as carrier for drug delivery and vaccine construction

Y Tan, L Chen, K Li, B Lou, Y Liu, Z Liu - Journal of Controlled Release, 2022 - Elsevier
Yeast has been employed as an effective derived drug carrier as a unicellular
microorganism. Many research works have been devoted to the encapsulation of nucleic …

Molecular dynamics: new frontier in personalized medicine

P Sneha, CGP Doss - Advances in protein chemistry and structural biology, 2016 - Elsevier
The field of drug discovery has witnessed infinite development over the last decade with the
demand for discovery of novel efficient lead compounds. Although the development of novel …

Phenotype determines nanoparticle uptake by human macrophages from liver and blood

SA MacParland, KM Tsoi, B Ouyang, XZ Ma, J Manuel… - ACS …, 2017 - ACS Publications
A significant challenge to delivering therapeutic doses of nanoparticles to targeted disease
sites is the fact that most nanoparticles become trapped in the liver. Liver-resident …

A Potent Micron Neoantigen Tumor Vaccine GP‐Neoantigen Induces Robust Antitumor Activity in Multiple Tumor Models

Z Jing, S Wang, K Xu, Q Tang, W Li, W Zheng… - Advanced …, 2022 - Wiley Online Library
Therapeutic tumor neoantigen vaccines have been widely studied given their good safety
profile and ability to avoid central thymic tolerance. However, targeting antigen‐presenting …

Magnetic field-assisted aligned patterning in an alginate-silk fibroin/nanocellulose composite for guided wound healing

K Ganguly, H Jin, SD Dutta, DK Patel, TV Patil… - Carbohydrate …, 2022 - Elsevier
This study was focused on utilizing the magneto-responsiveness of cellulose nanocrystals
(CNCs) in an alginate-silk fibroin (ASF) matrix under a low-strength (0.28 T) magnetic field …

Entrapping of nanoparticles in yeast cell wall microparticles for macrophage-targeted oral delivery of cabazitaxel

T Ren, J Gou, W Sun, X Tao, X Tan… - Molecular …, 2018 - ACS Publications
In this work, a nano-in-micro carrier was constructed by loading polymer–lipid hybrid
nanoparticles (NPs) into porous and hollow yeast cell wall microparticles (YPs) for …

[HTML][HTML] Preparation and characterization of beta-glucan particles containing a payload of nanoembedded rifabutin for enhanced targeted delivery to macrophages

TK Upadhyay, N Fatima, D Sharma… - EXCLI …, 2017 - ncbi.nlm.nih.gov
Abstract β-glucan particles (GP) are polymeric carbohydrates, mainly found as components
of cell wall fungi, yeast, bacteria and also in cereals such as barley and oat, and have been …

Polysaccharide dual coating of yeast capsules for stabilization of anthocyanins

C Tan, J Wang, B Sun - Food Chemistry, 2021 - Elsevier
The dual coated yeast capsules for anthocyanin encapsulation and stabilization were
fabricated. Anthocyanins were preloaded in hollow yeast capsules, and then the dual …

Curcumin encapsulation in yeast glucan particles promotes its anti-inflammatory potential in vitro

Z Plavcová, P Šalamúnová, I Saloň, F Štěpánek… - International Journal of …, 2019 - Elsevier
Abstract Glucan particles (GPs) from Saccharomyces cerevisiae are hollow shells that are
composed mainly of β-1, 3-d-glucan, which has demonstrated immunomodulatory and anti …

Nanotechnology in glycomics: applications in diagnostics, therapy, imaging, and separation processes

E Dosekova, J Filip, T Bertok, P Both… - Medicinal research …, 2017 - Wiley Online Library
This review comprehensively covers the most recent achievements (from 2013) in the
successful integration of nanomaterials in the field of glycomics. The first part of the paper …