Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …

Traumatic brain injury (TBI) is immediate damage caused by a blow to the head resulting
from traffic accidents, falls, and sporting activity, which causes death or serious disabilities in …

Injectable hydrogel has the advantage to fill the defective area and thereby shows promise
as therapeutic implant or cell/drug delivery vehicle for tissue repair. In this study, an …

The epilepsies are a diverse spectrum of disease states characterized by spontaneous
seizures and associated comorbidities. Neuron-focused perspectives have yielded an array …

Inflammatory processes induced by brain injury are important for recovery; however, when
uncontrolled, inflammation can be deleterious, likely explaining why most anti-inflammatory …

Ferroptosis is a novel regulated cell death characterized by metabolic disorders and iron-
dependent oxidative destruction of the lipid bilayer. It is primarily caused by the imbalance of …

This review outlined evidence that purinergic signaling is involved in the modulation of
blood-brain barrier (BBB) permeability. The functional and structural integrity of the BBB is …

Abstract Background The Rotarod test with commercial apparatus is widely used to assess
locomotor performance, balance and motor learning as well as the deficits resulting from …

The blood-brain barrier (BBB) acts as the crucial physical filtration structure in the central
nervous system. Here, we investigate the role of a specific subset of astrocytes in the …

Inflammation is a primary component of the central nervous system injury response.
Traumatic brain and spinal cord injury are characterized by a pronounced microglial …