The role of leptin in health and disease

AM Ramos-Lobo, J Donato Jr - Temperature, 2017 - Taylor & Francis
Leptin is a master regulator of energy balance and body adiposity. Additionally, leptin exerts
important control on glucose homeostasis, thermogenesis, autonomic nervous system and …

Metabolic functions of prolactin: Physiological and pathological aspects

F Lopez‐Vicchi, C De Winne, B Brie… - Journal of …, 2020 - Wiley Online Library
Prolactin is named after its vital role of promoting milk production during lactation, although it
has been implicated in multiple functions within the body, including metabolism and energy …

Characterization of the metabolic differences between male and female C57BL/6 mice

GO de Souza, F Wasinski, J Donato Jr - Life sciences, 2022 - Elsevier
Aims The present study aims to compare the responses between male and female C57BL/6
mice to multiple metabolic challenges to understand the importance of sex in the control of …

Biology of heat stress; the nexus between intestinal hyperpermeability and swine reproduction

EJ Mayorga, JW Ross, AF Keating, RP Rhoads… - Theriogenology, 2020 - Elsevier
Unfavorable weather conditions are one of the largest constraints to maximizing farm animal
productivity. Heat stress (HS), in particular, compromises almost every metric of profitability …

Metabolic and feeding adjustments during pregnancy

R Haddad-Tóvolli, M Claret - Nature Reviews Endocrinology, 2023 - nature.com
Eating behaviours are determined by the integration of interoceptive and environmental
inputs. During pregnancy, numerous physiological adaptations take place in the maternal …

SOCS3 as a future target to treat metabolic disorders

JAB Pedroso, AM Ramos-Lobo, J Donato - Hormones, 2019 - Springer
The suppressors of cytokine signaling (SOCS) are a group of eight proteins responsible for
preventing excessive cytokine signaling. Among this protein family, SOCS3 has received …

Prolactin promotes adipose tissue fitness and insulin sensitivity in obese males

X Ruiz-Herrera, EA de Los Ríos, JM Díaz… - …, 2017 - academic.oup.com
Excessive accumulation of body fat triggers insulin resistance and features of the metabolic
syndrome. Recently, evidence has accumulated that obesity, type 2 diabetes, and metabolic …

Roles of leptin in reproduction, pregnancy and polycystic ovary syndrome: consensus knowledge and recent developments

MJ Vázquez, A Romero-Ruiz, M Tena-Sempere - Metabolism, 2015 - Elsevier
As an essential function for perpetuation of species, reproduction, including puberty onset, is
sensitive to the size of body energy stores and the metabolic state of the organism …

Secretion and function of pituitary prolactin in evolutionary perspective

A Dobolyi, S Oláh, D Keller, R Kumari… - Frontiers in …, 2020 - frontiersin.org
The hypothalamo-pituitary system developed in early vertebrates. Prolactin is an ancient
vertebrate hormone released from the pituitary that exerts particularly diverse functions. The …

Distribution of growth hormone-responsive cells in the mouse brain

IC Furigo, M Metzger, PDS Teixeira… - Brain Structure and …, 2017 - Springer
Growth hormone (GH) exerts important biological effects primarily related to growth and
metabolism. However, the role of GH signaling in the brain is still elusive. To better …