Acute septic arthritis

ME Shirtliff, JT Mader - Clinical microbiology reviews, 2002 - Am Soc Microbiol
Acute septic arthritis may develop as a result of hematogenous seeding, direct introduction,
or extension from a contiguous focus of infection. The pathogenesis of acute septic arthritis …

Drug-induced liver injury

K Fisher, R Vuppalanchi… - Archives of Pathology …, 2015 - meridian.allenpress.com
Context Drug-induced liver injury (DILI) represents a diverse set of responses following
exposure to any manufactured or naturally occurring chemical compound. Drug-induced …

Adverse drug reactions in elderly patients

PA Routledge, MS O'mahony… - British journal of …, 2004 - Wiley Online Library
Many studies from around the world show a correlation between increasing age and
adverse drug reaction (ADR) rate, at least for some medical conditions. More than 80% of …

Histological patterns in drug-induced liver disease

R Ramachandran, S Kakar - Journal of clinical pathology, 2009 - jcp.bmj.com
The diagnosis of drug-induced liver injury (DILI) is a challenging problem, often confounded
by incomplete clinical information and the difficulty of eliciting exposure to herbal products …

[PDF][PDF] Phenotypic characterization of idiosyncratic drug‐induced liver injury: the influence of age and sex

MI Lucena, RJ Andrade, N Kaplowitz… - …, 2009 - Wiley Online Library
Increased age and female sex are suggested risk factors for drug‐induced hepatotoxicity
(DILI). We studied the influence of these variables on the propensity to develop DILI, as well …

Drug-induced hepatotoxicity

WM Lee - New England Journal of Medicine, 1995 - Mass Medical Soc
Drug-induced liver injury is a potential complication of nearly every medication that is
prescribed, because the liver is central to the metabolic disposition of virtually all drugs and …

Drug hepatotoxicity

CY Chang, TD Schiano - Alimentary pharmacology & …, 2007 - Wiley Online Library
Background Drug toxicity is the leading cause of acute liver failure in the United States.
Further understanding of hepatotoxicity is becoming increasingly important as more drugs …

Hepatic safety of antibiotics used in primary care

RJ Andrade, PM Tulkens - Journal of Antimicrobial …, 2011 - academic.oup.com
Antibiotics used by general practitioners frequently appear in adverse-event reports of drug-
induced hepatotoxicity. Most cases are idiosyncratic (the adverse reaction cannot be …

Drug-induced liver disorders: implications for drug development and regulation

N Kaplowitz - Drug safety, 2001 - Springer
Drug-induced hepatotoxicity is a frequent cause of liver disease. Although often presenting
as acute hepatitis and/or cholestasis, virtually any clinicalpathological pattern of acute or …

HLA association of amoxicillin-clavulanate–induced hepatitis

ML Hautekeete, Y Horsmans, C van Waeyenberge… - Gastroenterology, 1999 - Elsevier
Background & Aims: Drug-induced immunoallergic hepatitis typically affects a minority of
patients exposed to a particular drug. Its rarity is believed to be due to metabolic or …