Sleep deficiency and chronic pain: potential underlying mechanisms and clinical implications
Pain can be both a cause and a consequence of sleep deficiency. This bidirectional
relationship between sleep and pain has important implications for clinical management of …
relationship between sleep and pain has important implications for clinical management of …
[HTML][HTML] The differential effects of sleep deprivation on pain perception in individuals with or without chronic pain: A systematic review and meta-analysis
Many experimental sleep deprivation (SD) studies were conducted to clarify the causal
relationship between sleep and pain. This systematic review and meta-analysis aimed to …
relationship between sleep and pain. This systematic review and meta-analysis aimed to …
The effect of sleep deprivation on pain perception in healthy subjects: a meta-analysis
Background There is strong evidence indicating an interaction between sleep and pain.
However, the size of this effect, as well as the clinical relevance, is unclear. Therefore, this …
However, the size of this effect, as well as the clinical relevance, is unclear. Therefore, this …
Decreased alertness due to sleep loss increases pain sensitivity in mice
Extended daytime and nighttime activities are major contributors to the growing sleep
deficiency epidemic,, as is the high prevalence of sleep disorders like insomnia. The …
deficiency epidemic,, as is the high prevalence of sleep disorders like insomnia. The …
Associations between sleep quality and migraine frequency: a cross-sectional case-control study
Migraine has been associated with sleep disturbances. Relationship between sleep quality
and migraine frequency is yet to be determined. The present study aimed to investigate …
and migraine frequency is yet to be determined. The present study aimed to investigate …
Bidirectional relationship between opioids and disrupted sleep: putative mechanisms
Millions of Americans suffer from opiate use disorder, and over 100 die every day from
opioid overdoses. Opioid use often progresses into a vicious cycle of abuse and withdrawal …
opioid overdoses. Opioid use often progresses into a vicious cycle of abuse and withdrawal …
Parabrachial complex links pain transmission to descending pain modulation
The rostral ventromedial medulla (RVM) has a well-documented role in pain modulation and
exerts antinociceptive and pronociceptive influences mediated by 2 distinct classes of …
exerts antinociceptive and pronociceptive influences mediated by 2 distinct classes of …
Causal association of sleep disturbances and low back pain: a bidirectional two-sample Mendelian randomization study
G Luo, Y Yao, J Tao, T Wang, M Yan - Frontiers in Neuroscience, 2022 - frontiersin.org
Background Previous observational studies have shown that low back pain (LBP) often
coexists with sleep disturbances, however, the causal relationship remains unclear. In the …
coexists with sleep disturbances, however, the causal relationship remains unclear. In the …
The role of sex in sleep deprivation related changes of nociception and conditioned pain modulation
N Eichhorn, RD Treede, S Schuh-Hofer - Neuroscience, 2018 - Elsevier
Sex matters both in the clinical field of pain and sleep medicine. Sleep disturbances are
highly prevalent in chronic pain patients and have been shown to deteriorate the pain …
highly prevalent in chronic pain patients and have been shown to deteriorate the pain …
Endogenous opiates and behavior: 2016
RJ Bodnar - Peptides, 2018 - Elsevier
This paper is the thirty-ninth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2016 …
concerning the endogenous opioid system. It summarizes papers published during 2016 …