The immune microenvironment: a major player in human cancers

WH Fridman, R Remark, J Goc, NA Giraldo… - International archives of …, 2014 - karger.com
Cancer is a major public health issue and figures among the leading causes of death in the
world. Cancer development is a long process, involving the mutation, amplification or …

Cytotoxic response against Epstein Barr virus coexists with diffuse large B-cell lymphoma tolerogenic microenvironment: clinical features and survival impact

M Cohen, AG Vistarop, F Huaman, M Narbaitz… - Scientific Reports, 2017 - nature.com
Abstract Epstein–Barr Virus (EBV) is present in neoplastic cells of 15% of Asian and Latin-
American diffuse large B-cell lymphoma (DLBCL) patients. Even though a tolerogenic …

High levels of regulatory T cells in blood are a poor prognostic factor in patients with diffuse large B-cell lymphoma

C Chang, SY Wu, YW Kang, KP Lin… - American journal of …, 2015 - academic.oup.com
Objectives Host immunity likely plays a role in preventing progression of diffuse large B-cell
lymphoma (DLBCL). Analysis of host immune cells may provide useful information for …

HSP110 sustains chronic NF-κB signaling in activated B-cell diffuse large B-cell lymphoma through MyD88 stabilization

C Boudesco, E Verhoeyen, L Martin… - Blood, The Journal …, 2018 - ashpublications.org
Activated B-cell diffuse large B-cell lymphoma (ABC-DLBCL) is an aggressive
lymphoproliferative disorder involving chronic NF-κB activation. Several mutations in the …

Treatment-prognostication-adjustment a new therapeutic idea by analyzing T cell immune checkpoint in tumor microenvironment by algorithm: A bibliometric analysis

S Ma, X Wu, Z Wu, Q Zhao - Human Vaccines & …, 2023 - Taylor & Francis
To evaluate the temporal and spatial distribution of the knowledge network about tumor
microenvironment and prognoses and explore new research hot spots and trends. Articles …

Primary central nervous system diffuse large B‐cell lymphoma has poorer immune cell infiltration and prognosis than its peripheral counterpart

C Chang, CH Lin, AL Cheng, LJ Medeiros… - …, 2015 - Wiley Online Library
Aims Primary central nervous system (CNS) diffuse large B‐cell lymphoma (PCNSL) is an
ominous disease with a poor prognosis. The brain is an immune‐privileged sanctuary, and …

Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments

MJ Abraham, C Goncalves, P McCallum, V Gupta… - Cell & Bioscience, 2024 - Springer
Background The tumour microenvironment (TME) consists of tumour-supportive immune
cells, endothelial cells, and fibroblasts. PhenoCycler, a high-plex single cell spatial biology …

Peripheral blood T cell alterations in newly diagnosed diffuse large B cell lymphoma patients and their long-term dynamics upon rituximab-based …

S Battella, MC Cox, R La Scaleia, A Di Napoli… - Cancer Immunology …, 2017 - Springer
The importance of T cell-dependent immune responses in achieving long-term cure of
chemoimmunotherapy-treated cancer patients is underscored by the recently described …

[HTML][HTML] 弥漫性大B 细胞淋巴瘤化疗后外周血T 细胞亚群的动态变化

符铃遥, 张红宾 - Advances in Clinical Medicine, 2023 - hanspub.org
引言: 弥漫性大B 细胞淋巴瘤(Diffuse large B-cell lymphoma, DLBCL) 患者体内T
淋巴细胞亚群的转化和分布与疾病进展有关. CD4+ T 细胞亚群在体内启动和调节抗淋巴瘤免疫 …

Primary testicular diffuse large B-cell lymphoma: morphological and immunophenotypical study with characterization of the T-cell component of the tumor …

F Magnoli, I Ricotti, M Novario… - Leukemia & …, 2016 - Taylor & Francis
Primary testicular (PT) lymphoma accounts for about 1–2% of all non-Hodgkin lymphomas.
Albeit rare, this is the most common testicular malignancy occurring in men aged 60 or over …