Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics

DV Bhalani, B Nutan, A Kumar, AK Singh Chandel - Biomedicines, 2022 - mdpi.com
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …

[HTML][HTML] Nanostructured lipid carriers (NLCs) as drug delivery platform: Advances in formulation and delivery strategies

M Elmowafy, MM Al-Sanea - Saudi Pharmaceutical Journal, 2021 - Elsevier
NLCs have provoked the incessant impulsion for the development of safe and valuable drug
delivery systems owing to their exceptional physicochemical and then biocompatible …

Nanostructured lipid carriers (NLC) system: A novel drug targeting carrier

VR Salvi, P Pawar - Journal of Drug Delivery Science and Technology, 2019 - Elsevier
Lipid nanocarriers are developed as an alternative to polymeric nanoparticles, liposomes
and emulsions. Further, Nanostructured Lipid Nanocarriers are the second generation lipid …

Curcumin loaded nanostructured lipid carriers for enhanced skin retained topical delivery: optimization, scale-up, in-vitro characterization and assessment of ex-vivo …

VK Rapalli, V Kaul, T Waghule, S Gorantla… - European Journal of …, 2020 - Elsevier
Nanostructured lipid carriers (NLC) have become a promising drug delivery system for
topical delivery of drugs. Delivery of lipophilic drugs with improved stability and entrapment …

Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug deliveryapplications

M Pourmadadi, MM Eshaghi, S Ostovar… - Journal of Drug Delivery …, 2023 - Elsevier
The emergence of nanomedicine drugs as a result of the fast advancement of
nanotechnology offers enormous potential for improving cancer treatment strategies. The …

Pharmaceutical dispersion techniques for dissolution and bioavailability enhancement of poorly water-soluble drugs

X Zhang, H Xing, Y Zhao, Z Ma - Pharmaceutics, 2018 - mdpi.com
Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …

[HTML][HTML] Nanostructured lipid carriers and their potential applications for versatile drug delivery via oral administration

VN Thuy, TV Van, AH Dao, BJ Lee - OpenNano, 2022 - Elsevier
Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …

[HTML][HTML] Recent progress of lipid nanoparticles-based lipophilic drug delivery: focus on surface modifications

Y Seo, H Lim, H Park, J Yu, J An, HY Yoo, T Lee - Pharmaceutics, 2023 - mdpi.com
Numerous drugs have emerged to treat various diseases, such as COVID-19, cancer, and
protect human health. Approximately 40% of them are lipophilic and are used for treating …

Tailoring the multi-functional properties of phospholipids for simple to complex self-assemblies

T Waghule, RN Saha, A Alexander, G Singhvi - Journal of Controlled …, 2022 - Elsevier
The unique interfacial properties, huge diversity, and biocompatible nature of phospholipids
make them an attractive pharmaceutical excipient. The amphiphilic nature of these …

Bilosomes nanocarriers for improved oral bioavailability of acyclovir: A complete characterization through in vitro, ex-vivo and in vivo assessment

Z Saifi, M Rizwanullah, SR Mir, S Amin - Journal of Drug Delivery Science …, 2020 - Elsevier
Acyclovir (ACV) is an antiviral drug given as tablet that has variable and incomplete
absorption from the gastrointestinal tract. Also the absorption is saturated with multi-dose …