Patients with cancer have an increased risk of both arterial and venous thrombotic events
compared with the general population. Both the site and stage of cancer are known to …

Hyperthermia has demonstrated clinical success in improving the efficacy of both chemo-
and radio-therapy in solid tumors. Pre-clinical and clinical research studies have …

Aims The aim of this study was to study changes in coronary microcirculation status during
and after several cycles of anthracycline treatment. Methods and results Large-white male …

Background: Arterial stiffness, the expression of reduced arterial elasticity, is an effective
predictor of cardiovascular disorders. Oxidative stress is an imbalance between exposure to …

Anthracycline antineoplastic agents such as doxorubicin are widely used and highly
effective component of adjuvant chemotherapy for breast cancer and curative regimens for …

Chemotherapy plays an irreplaceable role in the treatment of various malignant tumors
today. The traditional drug formulations lack of selectivity, cause serious damage to normal …

BACKGROUND Trauma-induced coagulopathy (TIC) is commonly seen among patients with
severe injury. The dynamic process of TIC is characterized by variability of the features of the …

Malignant and cardiovascular disorders are the top causes of mortality worldwide. This
article reviews the main literature data and mechanisms linking hematologic malignancies …

Doxorubicin (Dox) is a widely utilized chemotherapeutic; however, it carries side effects,
including drug-induced immune thrombocytopenia (DITP) and increased risk of venous …

In clinical studies, platelet aggregation and risk of thrombosis are increased in patients after
doxorubicin treatment. However, the exact role of doxorubicin in platelet functions and …