[HTML][HTML] Anti-rheumatoid drugs advancements: New insights into the molecular treatment of rheumatoid arthritis

RB Mrid, N Bouchmaa, H Ainani, R El Fatimy… - Biomedicine & …, 2022 - Elsevier
Rheumatoid arthritis (RA) is one of more than 100 types of arthritis. This chronic autoimmune
disorder affects the lining of synovial joints in about 0.5% of people and may induce severe …

Recent innovations in topical delivery for management of rheumatoid arthritis: a focus on combination drug delivery

S Karnam, MR Donthi, AB Jindal, AT Paul - Drug Discovery Today, 2024 - Elsevier
Highlights•Elucidation of the intricate mechanism involved in the pathogenesis of
rheumatoid arthritis.•Combination delivery in clinical trials and preclinical models.•Topical …

Assessing the potential of lignin nanoparticles as drug carrier: synthesis, cytotoxicity and genotoxicity studies

L Siddiqui, J Bag, D Mittal, A Leekha, H Mishra… - International journal of …, 2020 - Elsevier
Lignin nanoparticles synthesis is among recent developments in lignin valorization
especially for biomedical applications. In this study, a new technique where complete self …

[HTML][HTML] Thermosensitive smart hydrogel of PEITC ameliorates the therapeutic efficacy in rheumatoid arthritis

P Haloi, S Chawla, VB Konkimalla - European Journal of Pharmaceutical …, 2023 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune condition that accompanies chronic
inflammation of joints with limited therapeutic options. Phenethyl isothiocyanate (PEITC), a …

Nanotechnology-empowered combination therapy for rheumatoid arthritis: principles, strategies, and challenges

S Ren, Y Xu, X Dong, Q Mu, X Chen, Y Yu… - Journal of …, 2024 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease with multifactorial etiology and intricate
pathogenesis. In RA, repeated monotherapy is frequently associated with inadequate …

γ-Cyclodextrin-metal organic frameworks as efficient microcontainers for encapsulation of leflunomide and acceleration of its transformation into teriflunomide

I Kritskiy, T Volkova, A Surov, I Terekhova - Carbohydrate polymers, 2019 - Elsevier
Abstract γ-Cyclodextrin-based metal-organic framework (γCD-MOF) crystals were
successfully synthesized using a vapor diffusion method. An applicability of γCD-MOF for …

Drug-delivery nanoparticles for bone-tissue and dental applications

T Higino, R França - Biomedical Physics & Engineering Express, 2022 - iopscience.iop.org
The use of nanoparticles as biomaterials with applications in the biomedical field is growing
every day. These nanomaterials can be used as contrast imaging agents, combination …

Hyaluronate-functionalized hydroxyapatite nanoparticles laden with methotrexate and teriflunomide for the treatment of rheumatoid arthritis

S Pandey, N Rai, A Mahtab, D Mittal, FJ Ahmad… - International Journal of …, 2021 - Elsevier
Rheumatoid arthritis (RA), an autoimmune inflammatory disorder is currently incurable.
Methotrexate and Teriflunomide are routinely prescribed drugs but their uses are limited due …

Combining nanotechnology with monoclonal antibody drugs for rheumatoid arthritis treatments

XK Chi, XL Xu, BY Chen, J Su, YZ Du - Journal of Nanobiotechnology, 2023 - Springer
Rheumatoid arthritis (RA) is a systemic immune disease characterized by synovial
inflammation. Patients with RA commonly experience significant damage to their hand and …

Nanomedicine Strategies for Anti‐Inflammatory Treatment of Noninfectious Arthritis

L Chen, Y Wang, L Sun, J Yan… - Advanced Healthcare …, 2021 - Wiley Online Library
Noninfectious arthritis (NIA) comprises a class of chronic and progressive inflammatory
disorders that require early‐stage management to prevent disease progression. The most …