Association of pharmacological treatments with long-term pain control in patients with knee osteoarthritis: a systematic review and meta-analysis
D Gregori, G Giacovelli, C Minto, B Barbetta, F Gualtieri… - Jama, 2018 - jamanetwork.com
Importance Even though osteoarthritis is a chronic and progressive disease,
pharmacological agents are mainly studied over short-term periods, resulting in unclear …
pharmacological agents are mainly studied over short-term periods, resulting in unclear …
Animal models of osteoarthritis: classification, update, and measurement of outcomes
EL Kuyinu, G Narayanan, LS Nair… - Journal of orthopaedic …, 2016 - Springer
Osteoarthritis (OA) is one of the most commonly occurring forms of arthritis in the world
today. It is a debilitating chronic illness causing pain and immense discomfort to the affected …
today. It is a debilitating chronic illness causing pain and immense discomfort to the affected …
Strategies for the prevention of knee osteoarthritis
Osteoarthritis (OA) has been thought of as a disease of cartilage that can be effectively
treated surgically at severe stages with joint arthroplasty. Today, OA is considered a whole …
treated surgically at severe stages with joint arthroplasty. Today, OA is considered a whole …
Intervertebral disc degeneration and osteoarthritis: a common molecular disease spectrum
Intervertebral disc degeneration (IDD) and osteoarthritis (OA) affecting the facet joint of the
spine are biomechanically interdependent, typically occur in tandem, and have considerable …
spine are biomechanically interdependent, typically occur in tandem, and have considerable …
[HTML][HTML] Knee osteoarthritis phenotypes and their relevance for outcomes: a systematic review
Objective To systematically review the literature for studies investigating knee osteoarthritis
(OA) phenotypes to examine what OA characteristics are relevant for phenotyping. Methods …
(OA) phenotypes to examine what OA characteristics are relevant for phenotyping. Methods …
Hip osteoarthritis: etiopathogenesis and implications for management
Highly prevalent among the elderly, hip osteoarthritis (OA) carries a heavy burden of
disease. Guidelines for the management of hip OA are often extrapolated from knee OA …
disease. Guidelines for the management of hip OA are often extrapolated from knee OA …
Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin
A Hosseinzadeh, SK Kamrava… - Journal of pineal …, 2016 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive erosion of
articular cartilage. As chondrocytes are the only cell type forming the articular cartilage, their …
articular cartilage. As chondrocytes are the only cell type forming the articular cartilage, their …
Efficacy of platelet-rich plasma injections in osteoarthritis of the knee: a systematic review and meta-analysis
ABM Laudy, EWP Bakker, M Rekers… - British journal of sports …, 2015 - bjsm.bmj.com
Background The effectiveness of platelet-rich plasma (PRP) injections for osteoarthritis (OA)
is still controversial. We investigated the effect of PRP injections in patients with knee OA …
is still controversial. We investigated the effect of PRP injections in patients with knee OA …
A current review of molecular mechanisms regarding osteoarthritis and pain
AS Lee, MB Ellman, D Yan, JS Kroin, BJ Cole… - Gene, 2013 - Elsevier
Osteoarthritis afflicts millions of individuals across the world resulting in impaired quality of
life and increased health costs. To understand this disease, physicians have been studying …
life and increased health costs. To understand this disease, physicians have been studying …
[HTML][HTML] Targeting the gut microbiome to treat the osteoarthritis of obesity
Obesity is a risk factor for osteoarthritis (OA), the greatest cause of disability in the US. The
impact of obesity on OA is driven by systemic inflammation, and increased systemic …
impact of obesity on OA is driven by systemic inflammation, and increased systemic …