Importance Even though osteoarthritis is a chronic and progressive disease,
pharmacological agents are mainly studied over short-term periods, resulting in unclear …

Osteoarthritis (OA) is one of the most commonly occurring forms of arthritis in the world
today. It is a debilitating chronic illness causing pain and immense discomfort to the affected …

Osteoarthritis (OA) has been thought of as a disease of cartilage that can be effectively
treated surgically at severe stages with joint arthroplasty. Today, OA is considered a whole …

Intervertebral disc degeneration (IDD) and osteoarthritis (OA) affecting the facet joint of the
spine are biomechanically interdependent, typically occur in tandem, and have considerable …

Objective To systematically review the literature for studies investigating knee osteoarthritis
(OA) phenotypes to examine what OA characteristics are relevant for phenotyping. Methods …

Highly prevalent among the elderly, hip osteoarthritis (OA) carries a heavy burden of
disease. Guidelines for the management of hip OA are often extrapolated from knee OA …

Osteoarthritis (OA) is a degenerative joint disease characterized by progressive erosion of
articular cartilage. As chondrocytes are the only cell type forming the articular cartilage, their …

Background The effectiveness of platelet-rich plasma (PRP) injections for osteoarthritis (OA)
is still controversial. We investigated the effect of PRP injections in patients with knee OA …

Osteoarthritis afflicts millions of individuals across the world resulting in impaired quality of
life and increased health costs. To understand this disease, physicians have been studying …

Obesity is a risk factor for osteoarthritis (OA), the greatest cause of disability in the US. The
impact of obesity on OA is driven by systemic inflammation, and increased systemic …