MRAS: a close but understudied member of the RAS family

LC Young, P Rodriguez-Viciana - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
MRAS is the closest relative to the classical RAS oncoproteins and shares most regulatory
and effector interactions. However, it also has unique functions, including its ability to …

MRAS in coronary artery disease—Unchartered territory

PW Shah, T Reinberger, S Hashmi, Z Aherrahrou… - IUBMB …, 2024 - Wiley Online Library
Genome‐wide association studies (GWAS) have identified coronary artery disease (CAD)
susceptibility locus on chromosome 3q22. 3. This locus contains a cluster of several genes …

Relationship between selected DNA polymorphisms and coronary artery disease complications

M Wirtwein, O Melander, M Sjőgren, M Hoffmann… - International Journal of …, 2017 - Elsevier
Background Coronary heart disease (CHD) development is complex in origin, with
contributions from well-defined lifestyle and not well-determined genetic risk factors. The aim …

The ANRIL genetic variants and their interactions with environmental risk factors on atherothrombotic stroke in a Han Chinese population

L Xiong, W Liu, L Gao, Q Mu, X Liu, Y Feng… - Journal of Stroke and …, 2018 - Elsevier
Background Ischemic stroke (IS) is considered to be a heterogeneous, multifactorial disease
with a strong genetic background. This study aims to determine whether variants in the …

The Effect of AMBP SNPs, Their Haplotypes, and Gene–Environment Interactions on the Risk of Atherothrombotic Stroke Among the Chinese Population

H Liu, D Luo, Y Qiu, Y Huang, C Chen… - Genetic Testing and …, 2019 - liebertpub.com
Background/Objectives: Ischemic stroke (IS) is a severe and complex disorder with high
morbidity and mortality rates and it has been associated with both environmental and …

A lack of association between the IKZF2 rs12619285 polymorphism and coronary heart disease

H Ye, Q Hong, Y Li, X Xu, YI Huang… - Experimental and …, 2015 - spandidos-publications.com
The IKZF2 rs12619285 polymorphism is associated with the eosinophil count, which has
multidimensional functions in the pathogenesis of coronary heart disease (CHD). The aim of …

[PDF][PDF] Association between the LXRα polymorphism and stroke in a Chinese population

JS Yang, JJ Hao, SS Wang, ZF Zhu, Q Fang, H Bao… - Genet Mol …, 2015 - funpecrp.com.br
We examined the relationship between the liver X receptor α gene (LXRα) polymorphism
and the susceptibility to stroke. We utilized the single fluorescent-labeled probe technique to …

Association studies of candidate single-nucleotide polymorphisms with Symptomatic Intracranial Atherosclerotic Stenosis in a Chinese Han population

F Yu, X Zhou, S Zeng, X Feng, Z Li, J Wang, Q Zhan… - 2019 - researchsquare.com
Background: Genetic factors underlying predisposition to Symptomatic Intracranial
Atherosclerotic Stenosis (sICAS) remain unknown, the purpose of the present study was to …

The research on association of copy number variation in chromosome 9p21 region with atherothrombotic stroke in the Han Chinese population

H Liu, M Yang, X Wang, Y Ji, J Zhao, W Liu… - Journal of the …, 2017 - Elsevier
Background/purpose The copy number variants (CNVs) contain more genetic information
compared with SNPs. The aim of this study was to elucidate whether the CNVs in …

[引用][C] MRAS 基因多态性与青年缺血性卒中患者的关系

白文, 张治中, 曹立平, 李芸, 王昭君, 林颖, 刘新峰… - 中国脑血管病杂志, 2014