Biomacromolecular therapeutic agents, particularly proteins, antigens, enzymes, and nucleic
acids are emerging as powerful candidates for the treatment of various diseases and the …

CD44 is a cell surface adhesion molecule, which is overexpressed on cancer stem cells.
The interaction of CD44 with hyaluronan is responsible for tumor development, metastasis …

Abstract BACH1 (BTB and CNC homology 1, basic leucine zipper transcription factor 1) is a
transcriptional factor and a member of cap 'n'collar (CNC) and basic region leucine zipper …

The use of viral vectors in gene therapy has many disadvantages that have been widely
described. The development of new nonviral vectors using safe polymers such as chitosan …

AIM: In the present investigation, vancomycin (VCM) biodegradable nanoparticles were
developed for oral administration, with the aim of improving its intestinal permeability …

Over the past decade, there have been remarkable advances in understanding the signaling
pathways involved in cancer development. It is well-established that cancer is caused by the …

A controlled release delivery system helps to overcome the problem of short life of the
leutinizing hormone releasing hormone (LHRH) in blood and avoids use of multiple …

In current times, DNA vaccines are seen as a promising approach to treat and prevent
diseases, such as virus infections and cancer. Aiming at the production of a functional and …

Recently, promising strategies of plexes include the complexation of nucleic acids with lipids
(lipoplexes) and different kinds of polymers (polyplexes) for delivery of actives and genetic …

Background: Despite therapeutics based on siRNA have an immense potential for the
treatment of incurable diseases such as cancers. However, the in vivo utilization of siRNA …