Abstract Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited,
neurodegenerative disease. It can manifest either with a cerebellar syndrome or as …

Maintenance of homeostasis is pivotal to all forms of life. In the case of plants, homeostasis
is constantly threatened by the inability to escape environmental fluctuations, and therefore …

RNA binding proteins (RBPs) control the fate and expression of a transcriptome. Despite this
fundamental importance, our understanding of plant RBPs is rudimentary, being mainly …

Protein synthesis is a fundamental process in gene expression that depends upon the
abundance and accessibility of the mRNA transcript as well as the activity of many protein …

Translational control mechanisms are, besides transcriptional control and mRNA stability,
the most determining for final protein levels. A large number of accessory factors that assist …

Ataxin-2, the gene product of the Spinocerebellar Ataxia Type 2 (SCA2) gene, is a protein of
unknown function with abundant expression in embryonic and adult tissues. Its interaction …

Abstract Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant genetic disease
characterized by cerebellar dysfunction associated with slow saccades, early hyporeflexia …

RNA-binding proteins play fundamental roles in the regulation of molecular processes
critical to cellular and organismal homeostasis. Recent studies have identified the RNA …

mRNA–ribonucleoprotein (mRNP) complexes mediate post-transcriptional control
mechanisms in the cell nucleus and cytoplasm. Transcriptional control is paramount to gene …

Parental imprinting is important for seed development, but few imprinted genes have been
identified in plants. The four known imprinted genes in Arabidopsis thaliana encode …