Commentary on Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: relevance in infectious diseases and vaccination studies in human …
In their recent publication, Khatri et al.[1] describe an immunoglobulin germline gene
database inferred from short-read genomic sequence data derived from five …
database inferred from short-read genomic sequence data derived from five …
The multilevel extensive diversity across the cynomolgus macaque captured by ultra-deep adaptive immune receptor repertoire sequencing
Y Zhu, H Tang, W Xie, S Chen, H Zeng, C Lan… - Science …, 2024 - science.org
The extent to which AIRRs differ among and within individuals remains elusive. Via ultra-
deep repertoire sequencing of 22 and 25 tissues in three cynomolgus macaques …
deep repertoire sequencing of 22 and 25 tissues in three cynomolgus macaques …
Poorly expressed alleles of several human immunoglobulin heavy chain variable genes are common in the human population
M Ohlin - Frontiers in immunology, 2021 - frontiersin.org
Extensive diversity has been identified in the human heavy chain immunoglobulin locus,
including allelic variation, gene duplication, and insertion/deletion events. Several genes …
including allelic variation, gene duplication, and insertion/deletion events. Several genes …
Characterizing the dynamics of BCR repertoire from repeated influenza vaccination
G Mai, C Zhang, C Lan, J Zhang, Y Wang… - Emerging Microbes & …, 2023 - Taylor & Francis
Yearly epidemics of seasonal influenza cause an enormous disease burden around the
globe. An understanding of the rules behind the immune response with repeated …
globe. An understanding of the rules behind the immune response with repeated …
[HTML][HTML] IMGT® Biocuration and Analysis of the Rhesus Monkey IG Loci
V Nguefack Ngoune, M Bertignac, M Georga… - Vaccines, 2022 - mdpi.com
The adaptive immune system, along with the innate immune system, are the two main
biological processes that protect an organism from pathogens. The adaptive immune system …
biological processes that protect an organism from pathogens. The adaptive immune system …
Novel polymorphic and copy number diversity in the antibody IGH locus of South African individuals
AA Marsden, M Corcoran, GK Hedestam, N Garrett… - Immunogenetics, 2025 - Springer
The heavy chain of an antibody is crucial for mediating antigen binding. IGHV genes, which
partially encode the heavy chain of antibodies, exhibit vast genetic diversity largely through …
partially encode the heavy chain of antibodies, exhibit vast genetic diversity largely through …
Assessing the Efficacy of Molecular, Serological, and Radiological Techniques for the Detection of SARS-CoV-2
U Aziz, A Sohail, M Yaseen, M Alam… - National Journal of Life and …, 2024 - njlhs.com
Due to the coronavirus episode numerous examinations are being led for remedial systems
and antibodies yet detection techniques assume a significant job in the control of the …
and antibodies yet detection techniques assume a significant job in the control of the …
Computational inference, validation, and analysis of 5'UTR-leader sequences of alleles of immunoglobulin heavy chain variable genes
Y Huang, L Thörnqvist, M Ohlin - Frontiers in Immunology, 2021 - frontiersin.org
Upstream and downstream sequences of immunoglobulin genes may affect the expression
of such genes. However, these sequences are rarely studied or characterized in most …
of such genes. However, these sequences are rarely studied or characterized in most …
Single-cell analysis reveals multi-faceted features of B cell development together with age-associated B cell subpopulations
X Yang, H Tang, C Lan, W He, S Chen, H Zeng, D Liu… - bioRxiv, 2024 - biorxiv.org
The development and maturation of B lymphocytes involve intricate orchestrated processes,
where dedicated gene regulations (GR) take place within specific microenvironments …
where dedicated gene regulations (GR) take place within specific microenvironments …