Venomous snakebite is considered the single most important cause of human injury from
venomous animals worldwide. Coagulopathy is one of the commonest important systemic …

Snakebite envenoming (SBE) is a priority neglected tropical disease, which kills in excess of
100,000 people per year. Additionally, many millions of survivors also suffer through …

The clinical and epidemiological features, as well as complications presented by 39 patients
with Bothrops, Porthidium and Bothriechis snakebites, are described. Patients were admitted …

Bothrops asper inflicts the majority of snakebites in Central America and in the northern
regions of South America, mostly affecting young agricultural workers in rural settings. This …

Hematologic abnormalities are the most common effects of snake envenoming globally.
Venom-induced consumption coagulopathy (VICC) is the commonest and most important …

Snake antivenoms are formulations of immunoglobulins, or immunoglobulin fragments,
purified from the plasma of animals immunized with snake venoms. Their therapeutic …

The parenteral administration of antivenoms is the cornerstone of snakebite envenoming
therapy. Efforts are made to ensure that antivenoms of adequate efficacy and safety are …

Background Envenoming from snakebites is most effectively treated by antivenom. However,
the antivenom available in South Asian countries commonly causes acute allergic reactions …

The concept of antivenoms was first developed by Henry Sewall in 1887 when he
demonstrated that pigeons could be immunized against the effects of pygmy rattlesnake …

The therapy of snakebite envenomation has been based on the parenteral administration of
animal-derived antivenoms. Despite the success of this treatment at reducing the impact of …