Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings

P Majumdar, A Pati, M Patra, RK Behera… - Chemical …, 2014 - ACS Publications
Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but also to the …

Palladium-catalyzed synthesis of nitriles from N-phthaloyl hydrazones

Y Ano, M Higashino, Y Yamada… - Chemical …, 2022 - pubs.rsc.org
The Pd-catalyzed transformation of N-phthaloyl hydrazones into nitriles involving the
cleavage of an N–N bond is reported. The use of N-heterocyclic carbene as a ligand is …

Regioselective synthesis and biological evaluation of some novel thiophene-containing heterocyclic scaffolds as potential chemotherapeutic agents

HM Gaber, MC Bagley - European Journal of Chemistry, 2011 - eurjchem.com
In the reaction of 2-amino-3-carbethoxythiophene derivative 2b with hydrazine hydrate the
respective aminocarbohydrazide 3 was isolated. Treatment of the latter product with carbon …

[PDF][PDF] A facile and convenient method to the one-pot synthesis of 2-mercapto-4 (3h)-quinazolinones

F Nikpour, R Mozafari, T Paibast - Heterocycles, 2009 - triggered.stanford.clockss.org
2-Mercapto-4 (3H)-quinazolinone derivatives represent one of the most active classes of
heterocycles possessing a wide spectrum of industrial1 and biological activities. 2-5 Due to …

Synthesis and antimicrobial screening of some 1, 3, 4-oxadiazoles and their molecular properties prediction through'rule of five'.

PK Upadhyay, P Mishra - Pakistan Journal of …, 2019 - search.ebscohost.com
In the current study, a series of 5-(4-substituted phenyl)-1, 3, 4-oxadiazole-2-thiols (4a-h)
were prepared from 4-substituted benzoic acid hydrazides (3a-h). The chemical structures of …

[PDF][PDF] One-pot Synthesis, Molecular Modeling and In Vitro Antibacterial Activity of Novel 3-(1, 3, 4-Oxadiazol-2-yl) Quinoxaline 1, 4-Dioxide and Pyrazolyl Analogs.

MA Waly, L Abou-Zeid, SR El-Gogary… - Acta Chimica …, 2012 - researchgate.net
Abstract The new 1, 3, 4-oxadiazolylquinoxaline ring system was synthesized by the
condensation of the quinoxaline 1, 4-dioxide acid hydrazide 6 with acetyl chloride in one-pot …

Synthesis, antibacterial, and DNA-PK evaluation of some novel 6-fluoro-7-(cyclic amino)-2-(thioxo or oxo)-3-substituted quinazolin-4-ones as structural analogues of …

JT Heppell, JMA Al-Rawi - Medicinal Chemistry Research, 2015 - Springer
Abstract Quinolones, isothiazoloquinolone, and quinazolin-2, 4-diones represent a series of
potent antibacterial agents. In this investigation, a series of novel 6-fluoro-7-(cyclic amino)-1 …

[PDF][PDF] Synthesis, Antimicrobial and Cytotoxic Activities of Some Bio-isosteres of 1, 3, 4-Oxadiazoles

PK Upadhyay, P Mishra - Int J Chem Sci, 2017 - researchgate.net
Abstract In the present study, 5-(4-substituted phenyl)-1, 2, 4-triazole-3-thiol (5a-e) were
synthesized from 5-(4-substituted phenyl)-1, 3, 4-oxadiazole-2-thiol (4a-e) and their …

Synthesis of novel quinazolines as potential inhibitors of DNA-PK, PI3K, platelet aggregation, and bacterial propagation

JTE Heppell - 2014 - opal.latrobe.edu.au
Synthesis of Novel Quinazolines as Potential Inhibitors of DNA-PK, PI3K, Platelet
Aggregation, and Bacterial Propagation Page 1 Synthesis of Novel Quinazolines as …

Синтез 2H, 6H-піримідо [2, 1-b][1, 3, 4] тіадіазин-6-онів з кумариновим фрагментом та їх антимікробна активність

СМ Коваленко, СВ Власов, АІ Федосов… - Журнал органічної …, 2010 - dspace.nbuv.gov.ua
Нові похідні 2Н, 6Н-піримідо [2, 1-b][1, 3, 4] тіадіазин-6-онів з кумариновою ланкою були
одержані в результаті взаємодії 3-(α-бромацетил) кумаринів з З-аміно-2-тіоксо-1, 2, 3, 4 …