Mechanical properties of whole-body soft human tissues: a review

G Singh, A Chanda - Biomedical Materials, 2021 - iopscience.iop.org
The mechanical properties of soft tissues play a key role in studying human injuries and their
mitigation strategies. While such properties are indispensable for computational modelling …

Fifty shades of brain: a review on the mechanical testing and modeling of brain tissue

S Budday, TC Ovaert, GA Holzapfel… - … Methods in Engineering, 2020 - Springer
Brain tissue is not only one of the most important but also the most complex and compliant
tissue in the human body. While long underestimated, increasing evidence confirms that …

Materials and technologies for soft implantable neuroprostheses

SP Lacour, G Courtine, J Guck - Nature Reviews Materials, 2016 - nature.com
Implantable neuroprostheses are engineered systems designed to restore or substitute
function for individuals with neurological deficits or disabilities. These systems involve at …

Brain stiffness increases with myelin content

J Weickenmeier, R de Rooij, S Budday, P Steinmann… - Acta biomaterialia, 2016 - Elsevier
Brain stiffness plays an important role in neuronal development and disease, but reported
stiffness values vary significantly for different species, for different brains, and even for …

Nanoindentation of soft biological materials

L Qian, H Zhao - Micromachines, 2018 - mdpi.com
Nanoindentation techniques, with high spatial resolution and force sensitivity, have recently
been moved into the center of the spotlight for measuring the mechanical properties of …

Mechanobiology of the brain in ageing and Alzheimer's disease

CM Hall, E Moeendarbary… - European Journal of …, 2021 - Wiley Online Library
Just as the epigenome, the proteome and the electrophysiological properties of a cell
influence its function, so too do its intrinsic mechanical properties and its extrinsic …

Mechanical characterization of human brain tumors from patients and comparison to potential surgical phantoms

DC Stewart, A Rubiano, K Dyson, CS Simmons - PloS one, 2017 - journals.plos.org
While mechanical properties of the brain have been investigated thoroughly, the mechanical
properties of human brain tumors rarely have been directly quantified due to the …

Nano-mechanical signature of brain tumours

G Ciasca, TE Sassun, E Minelli, M Antonelli, M Papi… - Nanoscale, 2016 - pubs.rsc.org
Glioblastoma (GBM) and meningothelial meningioma (MM) are the most frequent malignant
and benign brain lesions, respectively. Mechanical cues play a major role in the progression …

Acute and chronic demyelinated CNS lesions exhibit opposite elastic properties

MM Urbanski, MB Brendel, CV Melendez-Vasquez - Scientific reports, 2019 - nature.com
Increased deposition of extracellular matrix (ECM) is a known inhibitor of axonal regrowth
and remyelination. Recent in vitr o studies have demonstrated that oligodendrocyte …

Physical and mechanical characterization of fibrin-based bioprinted constructs containing drug-releasing microspheres for neural tissue engineering applications

R Sharma, R Kirsch, KP Valente, MR Perez… - Processes, 2021 - mdpi.com
Three-dimensional bioprinting can fabricate precisely controlled 3D tissue constructs. This
process uses bioinks—specially tailored materials that support the survival of incorporated …