The evolving landscape of antibody–drug conjugates: In depth analysis of recent research progress

JM Sasso, R Tenchov, R Bird, KA Iyer… - Bioconjugate …, 2023 - ACS Publications
Antibody–drug conjugates (ADCs) are targeted immunoconjugate constructs that integrate
the potency of cytotoxic drugs with the selectivity of monoclonal antibodies, minimizing …

[HTML][HTML] Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies

S Hawas, AD Verderosa, M Totsika - Frontiers in cellular and infection …, 2022 - frontiersin.org
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …

[HTML][HTML] Staphylococcal biofilms: Challenges and novel therapeutic perspectives

C Kranjec, D Morales Angeles, M Torrissen Mårli… - Antibiotics, 2021 - mdpi.com
Staphylococci, like Staphylococcus aureus and S. epidermidis, are common colonizers of
the human microbiota. While being harmless in many cases, many virulence factors result in …

[HTML][HTML] Sustainable phyto-fabrication of silver nanoparticles using Gmelina arborea exhibit antimicrobial and biofilm inhibition activity

S Chandrasekharan, G Chinnasamy, S Bhatnagar - Scientific Reports, 2022 - nature.com
Increase in bacterial resistance to commonly used antibiotics is a major public health
concern generating interest in novel antibacterial treatments. Aim of this scientific endeavor …

[HTML][HTML] Antimicrobial resistance in biofilms: Exploring marine actinobacteria as a potential source of antibiotics and biofilm inhibitors

N Goel, SW Fatima, S Kumar, R Sinha, SK Khare - Biotechnology Reports, 2021 - Elsevier
Antimicrobial resistance (AMR) is one of the serious global public health threats that require
immediate action. With the emergence of new resistance mechanisms in infection-causing …

[HTML][HTML] The association between biofilm formation and antimicrobial resistance with possible ingenious bio-remedial approaches

Y Dutt, R Dhiman, T Singh, A Vibhuti, A Gupta… - Antibiotics, 2022 - mdpi.com
Biofilm has garnered a lot of interest due to concerns in various sectors such as public
health, medicine, and the pharmaceutical industry. Biofilm-producing bacteria show a …

[HTML][HTML] Antibiotic adjuvants: Synergistic tool to combat multi-drug resistant pathogens

V Kumar, N Yasmeen, A Pandey… - Frontiers in Cellular …, 2023 - frontiersin.org
The rise of multi-drug resistant (MDR) pathogens poses a significant challenge to the field of
infectious disease treatment. To overcome this problem, novel strategies are being explored …

In Vitro Evaluation of Antimicrobial Peptides from the Black Soldier Fly (Hermetia Illucens) against a Selection of Human Pathogens

L Van Moll, J De Smet, A Paas, D Tegtmeier… - Microbiology …, 2022 - Am Soc Microbiol
Antimicrobial peptides (AMPs) are being explored as alternatives to traditional antibiotics to
combat the rising antimicrobial resistance. Insects have proven to be a valuable source of …

Mixed biofilms of pathogenic Candida-bacteria: regulation mechanisms and treatment strategies

F Khan, NI Bamunuarachchi, DTN Pham… - Critical reviews in …, 2021 - Taylor & Francis
Mixed-species biofilm is one of the most frequently recorded clinical problems. Mixed
biofilms develop as a result of interactions between microorganisms of a single or multiple …

[HTML][HTML] Bioprospecting the skin microbiome: advances in therapeutics and personal care products

K Nicholas-Haizelden, B Murphy, M Hoptroff… - Microorganisms, 2023 - mdpi.com
Bioprospecting is the discovery and exploration of biological diversity found within
organisms, genetic elements or produced compounds with prospective commercial or …