Diaphragm dysfunction in critical illness

GS Supinski, PE Morris, S Dhar, LA Callahan - Chest, 2018 - Elsevier
The diaphragm is the major muscle of inspiration, and its function is critical for optimal
respiration. Diaphragmatic failure has long been recognized as a major contributor to death …

[HTML][HTML] Assessing breathing effort in mechanical ventilation: physiology and clinical implications

H de Vries, A Jonkman, ZH Shi… - Annals of …, 2018 - ncbi.nlm.nih.gov
Recent studies have shown both beneficial and detrimental effects of patient breathing effort
in mechanical ventilation. Quantification of breathing effort may allow the clinician to titrate …

[HTML][HTML] Diaphragm function and weaning from mechanical ventilation: an ultrasound and phrenic nerve stimulation clinical study

M Dres, EC Goligher, BP Dubé, E Morawiec… - Annals of Intensive …, 2018 - Springer
Background Diaphragm dysfunction is defined by a value of twitch tracheal pressure in
response to magnetic phrenic stimulation (twitch pressure) amounting to less than 11 cmH 2 …

Risk factors for pediatric extubation failure: the importance of respiratory muscle strength

RG Khemani, T Sekayan, J Hotz, RC Flink… - Critical care …, 2017 - journals.lww.com
Objective: Respiratory muscle weakness frequently develops during mechanical ventilation,
although in children there are limited data about its prevalence and whether it is associated …

Functional assessment of the diaphragm by speckle tracking ultrasound during inspiratory loading

E Oppersma, N Hatam, J Doorduin… - Journal of applied …, 2017 - journals.physiology.org
Assessment of diaphragmatic effort is challenging, especially in critically ill patients in the
phase of weaning. Fractional thickening during inspiration assessed by ultrasound has been …

[HTML][HTML] Comparison of clinical utility between diaphragm excursion and thickening change using ultrasonography to predict extubation success

JW Yoo, SJ Lee, JD Lee, HC Kim - The Korean journal of internal …, 2018 - ncbi.nlm.nih.gov
Methods This study included patients subjected to extubation trial in the medical or surgical
intensive care unit of a university-affiliated hospital from May 2015 through February 2016 …

[HTML][HTML] Estimation of the diaphragm neuromuscular efficiency index in mechanically ventilated critically ill patients

D Jansen, AH Jonkman, L Roesthuis, S Gadgil… - Critical Care, 2018 - Springer
Background Diaphragm dysfunction develops frequently in ventilated intensive care unit
(ICU) patients. Both disuse atrophy (ventilator over-assist) and high respiratory muscle effort …

[HTML][HTML] Strategies to optimize respiratory muscle function in ICU patients

WJM Schellekens, HWH van Hees, J Doorduin… - Critical Care, 2016 - Springer
Respiratory muscle dysfunction may develop rapidly in critically ill ventilated patients and is
associated with increased morbidity, length of intensive care unit stay, costs, and mortality …

Diaphragm dysfunction in mechanically ventilated patients

I Dot, P Pérez-Teran, MA Samper… - Archivos de …, 2017 - Elsevier
Muscle involvement is found in most critical patients admitted to the intensive care unit (ICU).
Diaphragmatic muscle alteration, initially included in this category, has been differentiated in …

[HTML][HTML] Diaphragm-protective mechanical ventilation to improve outcomes in ICU patients?

L Heunks, C Ottenheijm - American journal of respiratory and critical …, 2018 - atsjournals.org
The respiratory muscle pump drives alveolar ventilation. The diaphragm, a thin (2–3 mm in
healthy adults) dome-shaped muscle, is an essential component of the respiratory muscle …