Molecular mechanisms underlying cyclophosphamide-induced cognitive impairment and strategies for neuroprotection in preclinical models

KM Ibrahim, SF Darwish, EM Mantawy… - Molecular and Cellular …, 2024 - Springer
Cyclophosphamide has drastically enhanced the expectancy and quality of life of cancer
patients. However, it is accompanied by diverse neurological complications which are …

Piperlongumine: the amazing amide alkaloid from Piper in the treatment of breast cancer

S Mitra, P Biswas, A Bandyopadhyay… - Naunyn-Schmiedeberg's …, 2024 - Springer
Piperlongumine (PL), an alkaloid found primarily in the fruits and roots of the plant Piper
longum L.(Piperaceae), is a natural compound that exhibits potent activity against various …

[HTML][HTML] Unveiling the immunostimulatory potential of rhus Toxicodendron in immunocompromised Balb/C mice induced with cyclophosphamide

VP Saka, NK GV, BKR Sanapalli, A Goswami, A Roy… - Diseases, 2024 - mdpi.com
This study investigated how Rhus toxicodendron (RT)(6C, 30C, and 200C) can boost the
immune system of BALB/c mice that were given cyclophosphamide (CPM), which is an …

Temperature-Dependent Bioaccumulation, Metabolism, and Hepatotoxicity of Flufiprole in Lizards (Eremias argus)

J Chang, Q An, Y Xie, W Liu, P Xu… - … Science & Technology, 2023 - ACS Publications
As a phenylpyrazole insecticide, flufiprole is an important substitute for fipronil in the
agricultural field of China. However, its bioaccumulation and metabolism in terrestrial …

Tissue-specific variations of piperine in ten populations of Piper longum L.: bioactivities and toxicological profile

P Biswas, DK Pandey, MS Shekhawat, A Dey… - Scientific Reports, 2024 - nature.com
P. longum L., one of the most significant species of the genus Piperaceae, is most frequently
employed in Indian-Ayurvedic and other traditional medicinal-systems for treating a variety …

Protective potential of pterostilbene against cyclophosphamide-induced nephrotoxicity and cystitis in rats

G Kerimoğlu, T Arıcı, AF Bıyık, A Kulaber… - … Urology and Nephrology, 2023 - Springer
Purpose Cyclophosphamide (CYP) is an antitumor drug. However, in addition to its
antitumor affect, CYP can also lead to nephrotoxicity and hemorrhagic cystitis. The purpose …

Validation and Standardization of Gallic Acid and Ellagic Acid in Quercus Infectoria, Terminalia Chebula, and Pistacia Integerrima

AK Saini, S Zahiruddin, KG Newton… - Journal of AOAC …, 2023 - academic.oup.com
Background Due to its medicinal properties, Pistacia integerrima is in high demand and is
extensively used as a key ingredient in various formulations. However, its popularity has led …

Genotoxin Stress and the Role of Alkaloids

V Yadav, D Vohora - Adaptation under Stressful Environments through …, 2024 - Springer
Humans are subjected to an array of external and internal stimuli during their lives, which
injure genetic material and generate somatic mutations that lead to accumulating genomic …

Neratinib stimulates senescence of mammary cancer cells by reducing the levels of SIRT1

W Li, P Fu, P Shi, B Hu, H Li - Aging (Albany NY), 2024 - pmc.ncbi.nlm.nih.gov
Neratinib, a typical small-molecule, pan-human tyrosine kinase inhibitor (TKI), has been
licensed for the treatment of human epidermal growth factor receptor 2 (HER2)-positive …

The draft genome of Piper longum L.

D Mathew, R Valsalan - Crop Science, 2024 - Wiley Online Library
Genome of Piper longum (long pepper, Piperaceae), an important medicinal plant, is being
reported. The sequencing was carried out on Illumina Novaseq‐6000 platform at 150x …