Liposomes mimic natural cell membranes and have long been investigated as drug carriers
due to excellent entrapment capacity, biocompatibility and safety. Despite the success of …

Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …

It has been known that a considerable number of drugs in clinical use or under development
are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has …

As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

Mucus layer is a hydrophilic absorption barrier found in various regions of the body. The use
of particulate delivery systems showed potential in drug delivery to mucosal membranes by …

Thermoresponsive polymers have been investigated for a variety of clinical applications
which make use of in situ gelation at physiological temperatures. However, for biomedical …

It is believed that mucoadhesive surface properties on particles delivered to the
gastrointestinal (GI) tract improve oral absorption or local targeting of various difficult-to …

Throughout the past decade, there has been a rapid growth in the development of
protein/peptide-based therapeutics. These therapeutics have found widespread applications …

This article is aimed to overview the lipid-based nanostructures designed so far for the oral
administration of peptides and proteins, and to analyze the influence of their composition …