Abstract SARS-CoV-2, a novel coronavirus, is the agent responsible for the COVID-19
pandemic and is a major public health concern nowadays. The rapid and global spread of …

COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress
syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even …

In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

It has been reported that corticosteroid therapy was effective in the management of severe
acute respiratory syndrome (SARS) and the Middle East Respiratory Syndrome (MERS) …

Background Systemic corticosteroids are used to treat people with COVID‐19 because they
counter hyper‐inflammation. Existing evidence syntheses suggest a slight benefit on …

Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

The COVID-19 pandemic was caused by the recently emerged β-coronavirus SARS-CoV-2.
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide …

Abstract Purpose of Review Different treatment approaches have been described for the
management of COVID-19-related multisystem inflammatory syndrome in children (MIS-C) …

Hyperactivation of immune responses resulting in excessive release of pro-inflammatory
mediators in alveoli/lung structures is the principal pathological feature of coronavirus …