Type IV pili: paradoxes in form and function

L Craig, J Li - Current opinion in structural biology, 2008 - Elsevier
Type IV pili are filaments on the surfaces of many Gram-negative bacteria that mediate an
extraordinary array of functions, including adhesion, motility, microcolony formation and …

The structure and mechanism of the bacterial type II secretion system

S Naskar, M Hohl, M Tassinari… - Molecular …, 2021 - Wiley Online Library
The type II secretion system (T2SS) is a multi‐protein complex used by many bacteria to
move substrates across their cell membrane. Substrates released into the environment …

Architecture of the type IVa pilus machine

YW Chang, L Rettberg, A Treuner-Lange, J Iwasa… - Biophysical …, 2016 - cell.com
Type IV pili are part of a widespread superfamily of bacterial and archaeal cell surface
structures important for biofilm formation, motility, host adhesion, predation, DNA uptake …

Biogenesis of Pseudomonas aeruginosa type IV pili and regulation of their function

TL Leighton, RNC Buensuceso… - Environmental …, 2015 - Wiley Online Library
Summary Type IV pili (T4P) are bacterial virulence factors involved in a wide variety of
functions including deoxyribonucleic acid uptake, surface attachment, biofilm formation and …

Mechanism of assembly of type 4 filaments: everything you always wanted to know (but were afraid to ask)

V Pelicic - Microbiology, 2023 - microbiologyresearch.org
Type 4 filaments (T4F) are a superfamily of filamentous nanomachines–virtually ubiquitous
in prokaryotes and functionally versatile–of which type 4 pili (T4P) are the defining member …

The platform protein is essential for type IV pilus biogenesis

HK Takhar, K Kemp, M Kim, PL Howell… - Journal of Biological …, 2013 - ASBMB
A systematic genetic analysis was performed to identify the inner membrane proteins
essential for type IV pilus (T4P) expression in Pseudomonas aeruginosa. By inactivating the …

Architecture of the type II secretion and type IV pilus machineries

M Ayers, PL Howell, LL Burrows - Future microbiology, 2010 - Taylor & Francis
Motility and protein secretion are key processes contributing to bacterial virulence. A wealth
of phylogenetic, biochemical and structural evidence support the hypothesis that the widely …

Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'‐reductase related to old yellow enzyme

BV Adalbjörnsson, HS Toogood… - …, 2010 - Wiley Online Library
We report the crystal structure of a thermophilic “ene” reductase (TOYE) isolated from
Thermoanaerobacter pseudethanolicus E39. The crystal structure reveals a tetrameric …

Landmark discoveries and recent advances in type IV pilus research

PK Singh, J Little, MS Donnenberg - Microbiology and Molecular …, 2022 - Am Soc Microbiol
SUMMARY Type IV pili (T4P) are retractable multifunctional nanofibers present on the
surface of numerous bacterial and archaeal species. Their importance to microbiology is …

Meningococcal interactions with the host

E Carbonnelle, DJ Hill, P Morand, NJ Griffiths… - Vaccine, 2009 - Elsevier
Neisseria meningitidis interacts with host tissues through hierarchical, concerted and co-
ordinated actions of a number of adhesins; many of which undergo antigenic and phase …