Background Sinonasal neoplasms, whether benign and malignant, pose a significant
challenge to clinicians and represent a model area for multidisciplinary collaboration in …

Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with high propensity for
lymphatic spread and distant metastasis. It is prominent as an endemic malignancy in …

Immunotherapy combined with antiangiogenic targeted therapy has improved the treatment
of certain solid tumors, but effective regimens remain elusive for refractory …

Background QL1604 is a humanized immunoglobulin G4 monoclonal antibody against
programmed cell death protein 1. This first-in-human, open-label phase I study aimed to …

Single-agent checkpoint inhibitor (CPI) activity in Epstein-Barr Virus (EBV) related
nasopharyngeal carcinoma (NPC) is limited. Dual CPI shows increased activity in solid …

Epstein-Barr virus (EBV), one of the most common human viruses, has been associated with
both lymphoid and epithelial cancers. Undifferentiated nasopharyngeal carcinoma (NPC) …

This systematic review and meta-analysis investigates the predictive and prognostic role of
PD-L1 expression in treating head and neck squamous cell carcinoma (HNSCC) …

We aim to evaluate the efficacy and safety of anti-PD1 rechallenge in combination with anti-
angiogenesis or anti-EGFR treatment in recurrent/metastatic nasopharyngeal carcinoma …

Purpose The objective of this study was to investigate the risk of cardiovascular toxicities
related to PD-1/PD-L1 inhibitors in solid tumors. Methods A literature search was performed …

The identification of predictors for immunotherapy is often hampered by the absence of
control groups in many studies, making it difficult to distinguish between prognostic and …