The recently observed circadian oscillations of the intestinal microbiota underscore the
profound nature of the human–microbiome relationship and its importance for health …

The major archaeal membrane glycerolipids are distinguished from those of bacteria and
eukaryotes by the contrasting stereochemistry of their glycerol backbones, and by the use of …

The origin of eukaryotes was among the most important events in the history of life,
spawning a new evolutionary lineage that led to all complex multicellular organisms …

The existence of LUCA in the distant past is the logical consequence of the binary
mechanism of cell division. The biosphere in which LUCA and contemporaries were living …

Saccharolobus islandicus REY15A represents one of the very few archaeal models with
versatile genetic tools, which include efficient genome editing, gene silencing, and robust …

Archaeal cells are typically enveloped by glycosylated S-layer proteins. Archaeal protein
glycosylation provides valuable insights not only into their adaptation to their niches but also …

The work of Carl Woese and his colleagues of the Urbana University has been one of the
most important breakthroughs in biology in the last century (for historical sketches, see Refs …

Impact statement The applications of marker gene concatenation have been advanced to
resolve the key questions in the Tree of Life. However, the interphylum evolutionary …

While performed by all three domains of life, N-glycosylation in Archaea is less well
described than are the parallel eukaryal and bacterial processes. Still, what is known of the …

Observational and experimental discoveries of new factual entities such as objects, systems,
or processes, are major contributors to some advances in the life sciences. Yet, whereas …