MEIS transcription factors in development and disease

D Schulte, D Geerts - Development, 2019 - journals.biologists.com
ABSTRACT MEIS transcription factors are key regulators of embryonic development and
cancer. Research on MEIS genes in the embryo and in stem cell systems has revealed …

Identification of microRNA biomarkers in type 2 diabetes: a meta-analysis of controlled profiling studies

H Zhu, SW Leung - Diabetologia, 2015 - Springer
Aims/hypothesis The aim was to identify potential microRNA (miRNA) biomarkers of type 2
diabetes. Methods Controlled studies were retrieved from PubMed to compare miRNA …

MEIS1 and its potential as a cancer therapeutic target

M Yao, Y Gu, Z Yang, K Zhong… - … journal of molecular …, 2021 - spandidos-publications.com
Abstract Meis homeobox 1 (Meis1) was initially discovered in 1995 as a factor involved in
leukemia in an animal model. Subsequently, 2 years later, MEIS1, the human homolog, was …

[HTML][HTML] The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144

H Cai, Y Xue, P Wang, Z Wang, Z Li, Y Hu, Z Li… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Blood-tumor barrier (BTB) limits the delivery of chemotherapeutic agent to brain tumor
tissues. Long non-coding RNAs (lncRNAs) have been shown to play critical regulatory roles …

[HTML][HTML] MiR-144 inhibits proliferation and induces apoptosis and autophagy in lung cancer cells by targeting TIGAR

S Chen, P Li, J Li, Y Wang, Y Du, X Chen… - Cellular physiology and …, 2015 - karger.com
Background: MiRNAs are noncoding RNAs of 20-24 nucleotides that function as post-
transcriptional negative regulators of gene expression. MiRNA genes are usually …

Single and compound knock-outs of MicroRNA (miRNA)-155 and its angiogenic gene target CCN1 in mice alter vascular and neovascular growth in the retina via …

L Yan, S Lee, DR Lazzaro, J Aranda, MB Grant… - Journal of Biological …, 2015 - ASBMB
The response of the retina to ischemic insult typically leads to aberrant retinal
neovascularization, a major cause of blindness. The epigenetic regulation of angiogenic …

Role of epigenetics in zebrafish development

S Balasubramanian, A Raghunath, E Perumal - Gene, 2019 - Elsevier
The role of epigenetics in development has garnered attention in recent years due to their
ability to modulate the embryonic developmental gene expression in response to the …

Analysis of circulating miRNA expression profiles in type 2 diabetes patients with diabetic foot complications

G Fuentevilla-Alvarez, ME Soto… - International Journal of …, 2024 - mdpi.com
Type 2 diabetes mellitus (T2DM) is associated with various complications, including diabetic
foot, which can lead to significant morbidity and mortality. Non-healing foot ulcers in diabetic …

Mesenchymal Stem Cell‐Derived Microvesicles Support Ex Vivo Expansion of Cord Blood‐Derived CD34+ Cells

H Xie, L Sun, L Zhang, T Liu, L Chen… - Stem cells …, 2016 - Wiley Online Library
Mesenchymal stem cells (MSCs) are known to support the characteristic properties of
hematopoietic stem and progenitor cells (HSPCs) in the bone marrow hematopoietic …

[HTML][HTML] MicroRNA aberrations: An emerging field for gallbladder cancer management

V Chandra, JJ Kim, B Mittal, R Rai - World Journal of …, 2016 - ncbi.nlm.nih.gov
Gallbladder cancer (GBC) is infrequent but most lethal biliary tract malignancy characterized
by an advanced stage diagnosis and poor survival rates attributed to absence of specific …