CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb–based migration
Cells under high confinement form highly polarized hydrostatic pressure–driven, stable
leader blebs that enable efficient migration in low adhesion, environments. Here we …
leader blebs that enable efficient migration in low adhesion, environments. Here we …
Long range mutual activation establishes Rho and Rac polarity during cell migration
In migrating cells, the GTPase Rac organizes a protrusive front, whereas Rho organizes a
contractile back. How these GTPases are appropriately positioned at the opposite poles of a …
contractile back. How these GTPases are appropriately positioned at the opposite poles of a …