Toward a better understanding of the mechanisms and pathophysiology of anhedonia: are we ready for translation?

DA Pizzagalli - American Journal of Psychiatry, 2022 - Am Psychiatric Assoc
Anhedonia—the loss of pleasure or lack of reactivity to pleasurable stimuli—remains a
formidable treatment challenge across neuropsychiatric disorders. In major depressive …

Stress to inflammation and anhedonia: Mechanistic insights from preclinical and clinical models

CC Boyle, JE Bower, NI Eisenberger… - … & Biobehavioral Reviews, 2023 - Elsevier
Anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward
motivation, and/or deficits in reward-related learning, is a common feature of depression …

Positive affect treatment targets reward sensitivity: A randomized controlled trial.

MG Craske, AE Meuret, A Echiverri-Cohen… - Journal of consulting …, 2023 - psycnet.apa.org
Objective: Determine whether a novel psychosocial treatment for positive affect improves
clinical status and reward sensitivity more than a form of cognitive behavioral therapy that …

Dynamic influences on the neural encoding of social valence

N Padilla-Coreano, KM Tye… - Nature Reviews …, 2022 - nature.com
Social signals can serve as potent emotional triggers with powerful impacts on processes
from cognition to valence processing. How are social signals dynamically and flexibly …

[HTML][HTML] Mindfulness-Oriented Recovery Enhancement for addictive behavior, psychiatric distress, and chronic pain: A multilevel meta-analysis of randomized …

A Parisi, RL Roberts, AW Hanley, EL Garland - Mindfulness, 2022 - Springer
Abstract Objectives Mindfulness-Oriented Recovery Enhancement (MORE) is an integrative
intervention designed to ameliorate addiction, chronic pain, and psychiatric symptoms …

[HTML][HTML] How well do Cognitive Behavioural Therapy and Behavioural Activation for depression repair anhedonia? A secondary analysis of the COBRA randomized …

B Alsayednasser, E Widnall, H O'Mahen… - Behaviour research and …, 2022 - Elsevier
A secondary analysis of the COBRA randomized controlled trial was conducted to examine
how well Cognitive Behavioural Therapy (CBT) and Behavioural Activation (BA) repair …

The effect of ketamine on anhedonia: improvements in dimensions of anticipatory, consummatory, and motivation-related reward deficits

D Nogo, AK Jasrai, H Kim, F Nasri, F Ceban… - …, 2022 - Springer
Anhedonia is a common, persistent, and disabling condition. However, available
therapeutics primarily focus on the reduction of depressive and negative symptoms rather …

[HTML][HTML] Anhedonia and depressive disorders

A Serretti - Clinical Psychopharmacology and Neuroscience, 2023 - ncbi.nlm.nih.gov
Anhedonia is a core symptom of depression and of several psychiatric disorders. Anhedonia
has however expanded from its original definition to encompass a spectrum of reward …

Mindfulness-Oriented Recovery Enhancement remediates anhedonia in chronic opioid use by enhancing neurophysiological responses during savoring of natural …

EL Garland, ST Fix, JP Hudak, EM Bernat… - Psychological …, 2023 - cambridge.org
Background Neuropsychopharmacologic effects of long-term opioid therapy (LTOT) in the
context of chronic pain may result in subjective anhedonia coupled with decreased attention …

[HTML][HTML] Reducing anhedonia in major depressive disorder with future event specificity training (FEST): a randomized controlled trial

DJ Hallford, D Rusanov, JJE Yeow, DW Austin… - Cognitive Therapy and …, 2023 - Springer
Background Improving future thinking, such as characteristics of specificity, detail, and use of
mental imagery, may be one means to reduce anhedonia, particularly in a Major Depressive …