Polymeric micelles in cancer therapy: State of the art

B Ghosh, S Biswas - Journal of Controlled Release, 2021 - Elsevier
In recent years, polymeric micelles have been extensively utilized in pre-clinical studies for
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …

Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics

KR Gajbhiye, R Salve, M Narwade, A Sheikh… - Molecular Cancer, 2023 - Springer
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …

Thiol chitosan-wrapped gold nanoshells for near-infrared laser-induced photothermal destruction of antibiotic-resistant bacteria

P Manivasagan, F Khan, G Hoang, S Mondal… - Carbohydrate …, 2019 - Elsevier
Developing new antibacterial nanomaterials and novel therapeutic strategies for the
destruction of human pathogenic bacteria that cause infectious diseases is becoming more …

Anti-EGFR antibody conjugated thiol chitosan-layered gold nanoshells for dual-modal imaging-guided cancer combination therapy

P Manivasagan, SW Jun, G Hoang, S Mondal… - Journal of Controlled …, 2019 - Elsevier
Developing a novel multifunctional theranostic agent for cancer combination therapy has
attracted tremendous attention in recent years. In this report, we designed and developed a …

Redox-sensitive and hyaluronic acid-functionalized nanoparticles for improving breast cancer treatment by cytoplasmic 17α-methyltestosterone delivery

S Rezaei, S Kashanian, Y Bahrami, LJ Cruz, M Motiei - Molecules, 2020 - mdpi.com
Novel reduction-responsive hyaluronic acid–chitosan–lipoic acid nanoparticles (HACSLA-
NPs) were designed and synthesized for effective treatment of breast cancer by targeting …

A soft multifunctional film from chitosan modified with disulfide bond cross-links and prepared by a simple method

X Wang, Q Wang, P Wang, M Zhou, B Xu, Y Liu… - International Journal of …, 2023 - Elsevier
Chitosan was modified with thioctic acid and used to prepare soft films. As confirmed by
FTIR and XPS measurements, a condensation reaction occurred between the amino groups …

Bifunctional therapeutic application of low-frequency ultrasound associated with zinc phthalocyanine-loaded micelles

YA Martins, MJV Fonseca, TZ Pavan… - International Journal of …, 2020 - Taylor & Francis
Purpose Sonodynamic therapy (SDT) is a new therapeutic modality for the noninvasive
cancer treatment based on the association of ultrasound and sonosensitizer drugs. Topical …

Irinotecan-loaded polymeric micelles as a promising alternative to enhance antitumor efficacy in colorectal cancer therapy

FL Campos, J de Alcântara Lemos, CMR Oda… - Polymers, 2022 - mdpi.com
Colorectal cancer has been considered a worldwide public health problem since current
treatments are often ineffective. Irinotecan is a frontline chemotherapeutic agent that has …

Interface crosslinked mPEG-b-PAGE-b-PCL triblock copolymer micelles with high stability for anticancer drug delivery

Y Lu, X Gao, M Cao, B Wu, L Su, P Chen, J Miao… - Colloids and Surfaces B …, 2020 - Elsevier
The stability of polymeric micelles is a key property for anticancer drug delivery. In this study,
a novel amphiphilic triblock copolymer, methoxy poly (ethylene glycol)-b-poly (allyl glycidyl …

Mitochondrial Targeted Thermosensitive Nanocarrier for Near-Infrared-Triggered Precise Synergetic Photothermal Nitric Oxide Chemotherapy

M Wang, M Zhang, J Bi, J Li, X Hu… - … Applied Materials & …, 2024 - ACS Publications
Nitric oxide (NO) intervenes, that is, a potential treatment strategy, and has attracted wide
attention in the field of tumor therapy. However, the therapeutic effect of NO is still poor, due …