The phenomenal growth of global pharmaceutical sales and the quest for innovation are
driving an unprecedented search for human test subjects, particularly in middle-and low …

This book is about drugs, insanity, and society and about how changes in the relationship
between them cause changes in the ways we experience our selves. Insanity has always …

This volume's purpose is to describe concepts and methods concerning assessment of
health-related quality of life (HRQOL) in children and adolescents with a special focus on …

A look at how the concept of" risk factor" has influenced public health and preventive
medicine, with an emphasis upon the study of heart disease. The greatest revolutions in …

Equipoise is an essential condition to justify a clinical trial. The term, describes a state of
uncertainty: the data suggest but do not prove a drug's safety and efficacy The only way to …

The question of access to drugs in developing countries is at present largely influenced by
the TRIPS Agreement. TRIPS compliance in the field of health requires substantial changes …

I begin this commentary with an expanded typology of theories that endorse an internal
morality of medicine. I then subject these theories to a philosophical critique. I argue that the …

Placebo-controlled trials are held by many, including regulators at agencies like the United
States Food and Drug Administration (FDA), to be the gold standard in the assessment of …

Recent economic and political advances in developing countries on the African continent
and South East Asia are threatened by the rising death and morbidity rates of HIV/AIDS. In …

In 1998, 39 pharmaceutical manufacturers sued the government of South Africa to prevent
the implementation of a law designed to facilitate access to AIDS drugs at low cost. The …