Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis

JR Naglik, SJ Challacombe, B Hube - Microbiology and molecular …, 2003 - Am Soc Microbiol
Candida albicans is the most common fungal pathogen of humans and has developed an
extensive repertoire of putative virulence mechanisms that allows successful colonization …

Cell Wall and Secreted Proteins ofCandida albicans: Identification, Function, and Expression

WL Chaffin, JL Lopez-Ribot, M Casanova… - Microbiology and …, 1998 - Am Soc Microbiol
The cell wall is essential to nearly every aspect of the biology and pathogenicity of Candida
albicans. Although it was intially considered an almost inert cellular structure that protected …

[HTML][HTML] Cell biology of Candida albicans–host interactions

A da Silva Dantas, KK Lee, I Raziunaite… - Current opinion in …, 2016 - Elsevier
Highlights•The cell biology of Candida albicans is adapted both for life as a commensal and
as a pathogen.•C. albicans can either downregulate or upregulate virulence properties in …

Candida albicans Cell Wall Proteins

WLJ Chaffin - Microbiology and molecular biology reviews, 2008 - Am Soc Microbiol
The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …

Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels

AJP Brown, GD Brown, MG Netea, NAR Gow - Trends in microbiology, 2014 - cell.com
Metabolism is integral to the pathogenicity of Candida albicans, a major fungal pathogen of
humans. As well as providing the platform for nutrient assimilation and growth in diverse …

Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin

AH Verma, JP Richardson, C Zhou, BM Coleman… - Science …, 2017 - science.org
Candida albicans is a dimorphic commensal fungus that causes severe oral infections in
immunodeficient patients. Invasion of C. albicans hyphae into oral epithelium is an essential …

Hydrolytic enzymes as virulence factors of Candida albicans

M Schaller, C Borelli, HC Korting, B Hube - Mycoses, 2005 - Wiley Online Library
Candida albicans is a facultative pathogenic micro‐organism that has developed several
virulence traits enabling invasion of host tissues and avoidance of host defence …

The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

O Reuß, Å Vik, R Kolter, J Morschhäuser - Gene, 2004 - Elsevier
The construction of Candida albicans mutants by targeted gene disruption usually depends
on the use of nutritional markers for the selection of prototrophic transformants from …

Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans

S Biswas, P Van Dijck, A Datta - Microbiology and molecular …, 2007 - Am Soc Microbiol
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

D Sanglard, K Kuchler, F Ischer, JL Pagani… - Antimicrobial agents …, 1995 - Am Soc Microbiol
Azole antifungal agents, and especially fluconazole, have been used widely to treat
oropharyngeal candidiasis in patients with AIDS. An increasing number of cases of clinical …