Role of abnormal repolarization in the mechanism of cardiac arrhythmia

OE Osadchii - Acta physiologica, 2017 - Wiley Online Library
In cardiac patients, life‐threatening tachyarrhythmia is often precipitated by abnormal
changes in ventricular repolarization and refractoriness. Repolarization abnormalities …

QT interval measurement in ventricular pacing: implications for assessment of drug effects and pro-arrhythmia risk

JW Schurr, PK Grewal, R Fan, E Rashba - Journal of electrocardiology, 2022 - Elsevier
QT interval prolongation is a known risk factor for development of malignant ventricular
arrhythmias. Measurement of the QT interval is difficult in the setting of ventricular pacing …

Can spinal cord stimulation reduce ventricular arrhythmias?

R Grimaldi, A de Luca, L Kornet, D Castagno, F Gaita - Heart rhythm, 2012 - Elsevier
Methods The patients described below participated in a single-center clinical trial (SCS-
ICD), which was conducted from 2007 till 2011. The study was prematurely stopped owing to …

Preliminary study on left bundle branch area pacing in children: Clinical observation of 12 cases

D Wenlong, G Baojing, D Chencheng… - Journal of …, 2022 - Wiley Online Library
Introduction Left bundle branch area pacing (LBBAP) maintains electrical and mechanical
synchronization of the ventricles. It is a relatively physiological pacing mode, with low and …

[HTML][HTML] Rituximab-induced polymorphic ventricular tachycardia

JT Poterucha, M Westberg, P Nerheim… - Texas Heart Institute …, 2010 - ncbi.nlm.nih.gov
The anti-CD20 monoclonal antibody rituximab is an effective treatment for small lymphocytic
lymphoma; however, it has been associated with infusion reactions, including cardiac …

Na+ channel distribution and electrophysiological heterogeneities in guinea pig ventricular wall

OE Osadchii, E Soltysinska… - American Journal of …, 2011 - journals.physiology.org
We sought to explore the distribution pattern of Na+ channels across ventricular wall, and to
determine its functional correlates, in the guinea pig heart. Voltage-dependent Na+ channel …

QRS duration and QTc interval are predictors of risk for ventricular arrhythmias during cardiac resynchronization therapy

D Prochnau, H Kuehnert, HR Figulla, R Surber - Acta Cardiologica, 2011 - Taylor & Francis
Background and objectives QRS duration (QRSd) and prolonged corrected QT interval
(QTc) are associated with ventricular arrhythmic events. This study was designed to …

Acute effects of pacing site on repolarization and haemodynamics of the canine ventricles

AS Tsvetkova, NA Kibler, VP Nuzhny, DN Shmakov… - Europace, 2011 - academic.oup.com
Aims To determine the repolarization duration gradients in different ventricular regions at
atrial and ventricular pacing and to test the hypothesis that acute haemodynamic response …

Pro-Arrhythmic Effects of Discontinuous Conduction at the Purkinje Fiber-Ventricle Junction Arising From Heart Failure-Induced Ionic Remodeling–Insights From …

K Jian, C Li, JC Hancox, H Zhang - Frontiers in Physiology, 2022 - frontiersin.org
Heart failure is associated with electrical remodeling of the electrical properties and kinetics
of the ion channels and transporters that are responsible for cardiac action potentials …

[HTML][HTML] Potential pro-arrhythmic effect of cardiac resynchronization therapy

O Tayeh, W Farouk, A ElAzab, H Khald… - Journal of the Saudi Heart …, 2013 - Elsevier
A decline in mortality due to pump failure has been clearly documented after cardiac
resynchronization therapy (CRT), however the impact on sudden cardiac death and the …