Infection is a common cause of impaired fracture healing. In the clinical setting, definitive
fracture treatment and infection are often treated separately and sequentially, by different …

The development of novel therapeutics in the field of spinal neurosurgery faces a litany of
translational challenges. Achieving precise drug targeting within the confined spaces …

Although intra-articular vancomycin powder (VP) is sometimes applied before the closure of
the incision to prevent periprosthetic joint infection (PJI) after joint replacement, the dosage …

Objective A bone defect rat model was established to investigate the osteogenic effect of
local delivery two antibiotics (vancomycin and tobramycin powder) on bone regeneration …

Purpose The occurrence of surgical site infection (SSI) after lumbar spinal fusion is a serious
complication. Therefore, an increasing number of clinicians are applying vancomycin …

OBJECTIVE The use of intrawound vancomycin powder in spine surgery has been shown to
decrease the rate of surgical site infections; however, the optimal dose is unknown. High …

Study Design. Rat posterolateral lumbar fusion model. Objective. The aim of this study was
to compare the efficacy of freshly isolated adipose tissue-derived stromal vascular fraction (A …

Background Despite extensive research, there is still a need for safe and effective agents to
promote spinal fusion. Interleukin (IL)-1β is an important factor which influences the bone …

Fungal periprosthetic joint infections are an uncommon but potentially devastating
complication of arthroplasty surgery. The concurrent presence of a coexistent bacterial …

Abstract Study Design Cross-sectional study with systematic review of literature Objective
There is an increasing interest in the topical use of antibiotics to prevent infection following …