Objective To investigate whether people with subjective memory complaints (SMC) but no
objective deficits are at increased risk of developing mild cognitive impairment (MCI) and …

Over the last 20 years, evidence about the clinical correlates of cerebral white matter
changes (WMC; also called leukoaraiosis) has been accumulating. WMC are now listed …

Background Cerebral small vessel disease, a common cause of vascular dementia, is often
considered clinically silent before dementia or stroke become apparent. However, some …

Major depressive disorder (MDD) is a prevalent and recurring mental disorder often
associated with high rates of non-recovery and substantial consequences on psychosocial …

Objective: Subjective cognitive complaints are often used in the diagnosis of memory and
other cognitive impairment. This study examined whether cognitive complaints are …

Background: Cerebral small vessel disease (SVD) is a common cause of stroke, mild
cognitive impairment, dementia and physical impairments. Differences in SVD incidence or …

Dementia is characterized by a long preclinical phase that may last years to decades before
the onset of mild cognitive impairment. Slow gait speed and subjective memory complaint …

Objective: Whether subjective cognitive complaints are suggestive of depression or
concurrent cognitive impairment in older adults without dementia remains unclear. The …

Introduction Subjective cognitive decline (SCD) may indicate unhealthy cognitive changes,
but no standardized SCD measurement exists. This pilot study aimed to identify reliable …

The evidence on the clinical significance of cerebral white matter changes (WMC) has
mounted over the past few decades. WMC are recognized as one of the neuroimaging …