The field of biomedical optics has matured rapidly over the last decade and is poised to
make a significant impact on patient care. In particular, wide-field (typically> 5 cm), planar …

Spatial frequency domain imaging (SFDI) has witnessed very rapid growth over the last
decade, owing to its unique capabilities for imaging optical properties and chromophores …

The authors describe the development of diffuse optical imaging (DOI) technologies,
specifically the use of spatial and temporal modulation to control near infrared light …

Diffuse optical imaging probes deep living tissue enabling structural, functional, metabolic,
and molecular imaging. Recently, due to the availability of spatial light modulators, wide …

Oxygenation measurements are widely used in patient care. However, most clinically
available instruments currently consist of contact probes that only provide global monitoring …

A 1× 400 array of backside-illuminated SPADs fabricated in 130 nm 3D IC CMOS
technology is presented. Sensing is performed in the top tier substrate and time-to-digital …

We employ a clinical multiphoton microscope to monitor in vivo and noninvasively the
changes in reduced nicotinamide adenine dinucleotide (NADH) fluorescence of human …

Despite our understanding that the microvasculature plays a multifaceted role in the
development and progression of various conditions, we know little about the extent of this …

Spatial frequency-domain imaging (SFDI) utilizes multiple-frequency structured illumination
and model-based computation to generate two-dimensional maps of tissue absorption and …

A new optical acquisition scheme based on a pair of digital micromirror devices is
developed and applied to three-dimensional tomographic imaging of turbid media. By using …